Genetic deletion of dectin-1 does not affect the course of murine experimental colitis

Genetic deletion of dectin-1 does not affect the course of murine experimental colitis

<p>Abstract</p> <p>Background</p> <p>It is believed that inflammatory bowel diseases (IBD) result from an imbalance in the intestinal immune response towards the luminal microbiome. Dectin-1 is a widely expressed pattern recognition receptor that recognizes fungi and up...

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Bibliographic Details
Main Authors: Heinsbroek Sigrid EM, Oei Anneke, Roelofs Joris JTH, Dhawan Shobhit, te Velde Anje, Gordon Siamon, de Jonge Wouter J
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Gastroenterology
Subjects:
Dectin-1
Macrophages
Colitis
Innate immunity
Fungi
Intestine
Online Access:http://www.biomedcentral.com/1471-230X/12/33

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