Investigation of a Potential Pharmacokinetic Interaction Between Nebivolol and Fluvoxamine in Healthy Volunteers
Purpose: To investigate whether fluvoxamine coadministration can influence the pharmacokinetic properties of nebivolol and its active hydroxylated metabolite (4-OH-nebivolol) and to assess the consequences of this potential pharmacokinetic interaction upon nebivolol pharmacodynamics. Methods: This o...
Main Authors: | Ana-Maria Gheldiu, Laurian Vlase, Adina Popa, Corina Briciu, Dana Muntean, Corina Bocsan, Anca Buzoianu, Marcela Achim, Ioan Tomuta, Ioana Todor, Maria Neag |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-04-01
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Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/28287 |
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