Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central India
Purpose: To report on the microbiological profile and antibiotic sensitivity patterns of infectious keratitis at a tertiary center in central India. Methods: The suspected case of severe keratitis underwent microbiological culture and identification using the VITEK 2 technique. Antibiotic suscepti...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=6;spage=2455;epage=2459;aulast=Parmar |
| _version_ | 1797775074188591104 |
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| author | Gautam Singh Parmar Ashok Kumar Meena Prashant Borde Sonali Prasad |
| author_facet | Gautam Singh Parmar Ashok Kumar Meena Prashant Borde Sonali Prasad |
| author_sort | Gautam Singh Parmar |
| collection | DOAJ |
| description | Purpose: To report on the microbiological profile and antibiotic sensitivity patterns of infectious keratitis at a tertiary center in central India. Methods: The suspected case of severe keratitis underwent microbiological culture and identification using the VITEK 2 technique. Antibiotic susceptibility for different sensitivity and resistance patterns was analyzed. Demographics, clinical profile, and socioeconomic history was also documented. Results: Culture was positive in 233/455 (51.2%) patients. Pure bacterial growth was present in 83 (35.62%) patients and pure fungus was present in 146 (62.66%) patients. The most common bacterial cause of infectious keratitis was Pseudomonas followed by Staphylococcus and Bacillus. Pseudomonas showed 65%–75% resistance against levofloxacin, ceftazidime, imipenem, gentamycin, ciprofloxacin, and amikacin. Staphylococcus showed 65%–70% resistance against levofloxacin, erythromycin, and ciprofloxacin, with Streptococcus being 100% resistant to erythromycin. Conclusion: This study highlights the current trend of microbiological profiles of infectious keratitis and their antibiotic susceptibility at a rural setup in central India. Fungal predominance and increased resistance against the commonly used antibiotics were noted. |
| first_indexed | 2024-03-12T22:30:23Z |
| format | Article |
| id | doaj.art-3c67fc3de0424f47bca20c6e531f4fbf |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-03-12T22:30:23Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-3c67fc3de0424f47bca20c6e531f4fbf2023-07-21T15:15:02ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892023-01-017162455245910.4103/ijo.IJO_2070_22Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central IndiaGautam Singh ParmarAshok Kumar MeenaPrashant BordeSonali PrasadPurpose: To report on the microbiological profile and antibiotic sensitivity patterns of infectious keratitis at a tertiary center in central India. Methods: The suspected case of severe keratitis underwent microbiological culture and identification using the VITEK 2 technique. Antibiotic susceptibility for different sensitivity and resistance patterns was analyzed. Demographics, clinical profile, and socioeconomic history was also documented. Results: Culture was positive in 233/455 (51.2%) patients. Pure bacterial growth was present in 83 (35.62%) patients and pure fungus was present in 146 (62.66%) patients. The most common bacterial cause of infectious keratitis was Pseudomonas followed by Staphylococcus and Bacillus. Pseudomonas showed 65%–75% resistance against levofloxacin, ceftazidime, imipenem, gentamycin, ciprofloxacin, and amikacin. Staphylococcus showed 65%–70% resistance against levofloxacin, erythromycin, and ciprofloxacin, with Streptococcus being 100% resistant to erythromycin. Conclusion: This study highlights the current trend of microbiological profiles of infectious keratitis and their antibiotic susceptibility at a rural setup in central India. Fungal predominance and increased resistance against the commonly used antibiotics were noted.http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=6;spage=2455;epage=2459;aulast=Parmarantibiotic susceptibilityantimicrobial resistancecentral indiacorneal ulcerinfectious keratitis |
| spellingShingle | Gautam Singh Parmar Ashok Kumar Meena Prashant Borde Sonali Prasad Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central India Indian Journal of Ophthalmology antibiotic susceptibility antimicrobial resistance central india corneal ulcer infectious keratitis |
| title | Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central India |
| title_full | Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central India |
| title_fullStr | Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central India |
| title_full_unstemmed | Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central India |
| title_short | Microbial keratitis and antibiotic sensitivity patterns: A retrospective analysis at a tertiary center in Central India |
| title_sort | microbial keratitis and antibiotic sensitivity patterns a retrospective analysis at a tertiary center in central india |
| topic | antibiotic susceptibility antimicrobial resistance central india corneal ulcer infectious keratitis |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=6;spage=2455;epage=2459;aulast=Parmar |
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