Endometriosis in Adolescents with Obstructive Anomalies of the Reproductive Tract
Background: This study aimed to assess the prevalence and course of endometriosis in adolescents with obstructive Müllerian anomalies. Methods: The study group involved 50 adolescents undergoing surgeries (median age 13.5 (range 11.1–18.5)) for rare obstructive malformations of the genital tract: 15...
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| Format: | Article |
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MDPI AG
2023-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/5/2007 |
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| author | Karina Kapczuk Weronika Zajączkowska Klaudyna Madziar Witold Kędzia |
| author_facet | Karina Kapczuk Weronika Zajączkowska Klaudyna Madziar Witold Kędzia |
| author_sort | Karina Kapczuk |
| collection | DOAJ |
| description | Background: This study aimed to assess the prevalence and course of endometriosis in adolescents with obstructive Müllerian anomalies. Methods: The study group involved 50 adolescents undergoing surgeries (median age 13.5 (range 11.1–18.5)) for rare obstructive malformations of the genital tract: 15 girls had anomalies associated with cryptomenorrhea and 35 were menstruating. The median follow-up period was 2.4 (ranging from 0.1 to 9.5) years. Results: We diagnosed endometriosis in 23 of the 50 subjects (46%), including 10 of the 23 patients (43.5%) with obstructed hemivagina ipsilateral renal anomaly syndrome (OHVIRAS), six of eight patients (75%) with a unicornuate uterus with a non-communicating functional horn, two of three patients (66.7%) with distal vaginal aplasia, and five of five patients (100%) with cervicovaginal aplasia. Persistent dysmenorrhea, following treatment, affected 14 of the 50 adolescents (28%), including 8 of the 17 subjects (47.1%) diagnosed with endometriosis at the time of surgical correction and six adolescents diagnosed with endometriosis during the follow-up. Conclusions: Endometriosis affects about half of young adolescents undergoing surgical treatment of obstructive Müllerian anomalies after menarche. The incidence of endometriosis is highest in girls with cervical aplasia. The risk of developing endometriosis decreases after surgical correction of obstruction but is still significant in patients with uterine anomalies. |
| first_indexed | 2024-03-11T07:20:23Z |
| format | Article |
| id | doaj.art-3c68170193044c9db8a452f23e707146 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T07:20:23Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-3c68170193044c9db8a452f23e7071462023-11-17T08:01:21ZengMDPI AGJournal of Clinical Medicine2077-03832023-03-01125200710.3390/jcm12052007Endometriosis in Adolescents with Obstructive Anomalies of the Reproductive TractKarina Kapczuk0Weronika Zajączkowska1Klaudyna Madziar2Witold Kędzia3Division of Gynecology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, PolandGynecology and Obstetrics Clinical Hospital of Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, PolandDivision of Gynecology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, PolandDivision of Gynecology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, PolandBackground: This study aimed to assess the prevalence and course of endometriosis in adolescents with obstructive Müllerian anomalies. Methods: The study group involved 50 adolescents undergoing surgeries (median age 13.5 (range 11.1–18.5)) for rare obstructive malformations of the genital tract: 15 girls had anomalies associated with cryptomenorrhea and 35 were menstruating. The median follow-up period was 2.4 (ranging from 0.1 to 9.5) years. Results: We diagnosed endometriosis in 23 of the 50 subjects (46%), including 10 of the 23 patients (43.5%) with obstructed hemivagina ipsilateral renal anomaly syndrome (OHVIRAS), six of eight patients (75%) with a unicornuate uterus with a non-communicating functional horn, two of three patients (66.7%) with distal vaginal aplasia, and five of five patients (100%) with cervicovaginal aplasia. Persistent dysmenorrhea, following treatment, affected 14 of the 50 adolescents (28%), including 8 of the 17 subjects (47.1%) diagnosed with endometriosis at the time of surgical correction and six adolescents diagnosed with endometriosis during the follow-up. Conclusions: Endometriosis affects about half of young adolescents undergoing surgical treatment of obstructive Müllerian anomalies after menarche. The incidence of endometriosis is highest in girls with cervical aplasia. The risk of developing endometriosis decreases after surgical correction of obstruction but is still significant in patients with uterine anomalies.https://www.mdpi.com/2077-0383/12/5/2007endometriosisgenital tract anomaliesMüllerian anomaliesadolescentsOHVIRA syndromeunicornuate uterus |
| spellingShingle | Karina Kapczuk Weronika Zajączkowska Klaudyna Madziar Witold Kędzia Endometriosis in Adolescents with Obstructive Anomalies of the Reproductive Tract Journal of Clinical Medicine endometriosis genital tract anomalies Müllerian anomalies adolescents OHVIRA syndrome unicornuate uterus |
| title | Endometriosis in Adolescents with Obstructive Anomalies of the Reproductive Tract |
| title_full | Endometriosis in Adolescents with Obstructive Anomalies of the Reproductive Tract |
| title_fullStr | Endometriosis in Adolescents with Obstructive Anomalies of the Reproductive Tract |
| title_full_unstemmed | Endometriosis in Adolescents with Obstructive Anomalies of the Reproductive Tract |
| title_short | Endometriosis in Adolescents with Obstructive Anomalies of the Reproductive Tract |
| title_sort | endometriosis in adolescents with obstructive anomalies of the reproductive tract |
| topic | endometriosis genital tract anomalies Müllerian anomalies adolescents OHVIRA syndrome unicornuate uterus |
| url | https://www.mdpi.com/2077-0383/12/5/2007 |
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