Synthesis and Properties of Novel Poly(Hexyl-Substituted Lactides) for Pharmaceutical Applications

Synthesis and Properties of Novel Poly(Hexyl-Substituted Lactides) for Pharmaceutical Applications

Monohexyl-substituted lactide (mHLA) was synthesized by reaction of 2-hydroxyoctanoic acid with 2-bromopropionyl bromide, and polymerized with tin(II) 2-ethylhexanoate (Sn(Oct)2) or 4-dimethylaminopyridine (DMAP) in the presence of benzyl alcohol by ring-opening polymerization (ROP). Poly(...

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Bibliographic Details
Main Authors:	Thomas Trimaille, Robert Gurny, Michael Möller
Format:	Article
Language:	deu
Published:	Swiss Chemical Society 2005-06-01
Series:	CHIMIA
Subjects:	Degradation Injectable drug delivery system Polylactides Ring-opening polymerization
Online Access:	https://chimia.ch/chimia/article/view/4001

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