Human pluripotent stem cell (hPSC) and organoid models of autism: opportunities and limitations

Abstract Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder caused by genetic or environmental perturbations during early development. Diagnoses are dependent on the identification of behavioral abnormalities that likely emerge well after the disorder is established, leaving cri...

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Bibliographic Details
Main Authors: Savannah Kilpatrick, Courtney Irwin, Karun K. Singh
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02510-6