Imatinib attenuates neotissue formation during vascular remodeling in an arterial bioresorbable vascular graft

Imatinib attenuates neotissue formation during vascular remodeling in an arterial bioresorbable vascular graft

Background: Bioresorbable vascular grafts (BVGs) can transform biologically into active blood vessels and represent an alternative to traditional synthetic conduits, which are prone to complications such as infection and thrombosis. Although platelet-derived growth factors and c-Kit positive cells p...

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Bibliographic Details
Main Authors: Hideki Miyachi, MD, PhD, Shuhei Tara, MD, PhD, Satoru Otsuru, MD, PhD, Tai Yi, MD, Yong-Ung Lee, PhD, Joseph D. Drews, MD, Hidetaka Nakayama, PhD, Shinka Miyamoto, MD, PhD, Tadahisa Sugiura, MD, PhD, Toshihiro Shoji, BA, Christopher K. Breuer, MD, Toshiharu Shinoka, MD, PhD
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:JVS - Vascular Science
Subjects:
Tyrosine kinase inhibitor
Smooth muscle cell
Neotissue formation
Vascular remodeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2666350320300043

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