Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model

Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model

(-)-Epigallocatechin 3-gallate (EGCG) is the main active green tea catechin and has a wide variety of benefits for health. Post-traumatic osteoarthritis (PTOA) occurs as a consequence of joint injuries that commonly happen in the young population. In this study, we investigated the effects of EGCG o...

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Bibliographic Details
Main Authors: Hsuan-Ti Huang, Tsung-Lin Cheng, Cheng-Jung Ho, Han Hsiang Huang, Cheng-Chang Lu, Shu-Chun Chuang, Jhong-You Li, Tien-Ching Lee, Shih-Tse Chen, Yi-Shan Lin, Chih-Yao Lee, Lin Kang, Sung-Yen Lin, Chung-Hwan Chen
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
(-)-epigallocatechin 3-gallate (EGCG)
apoptosis
autophagy
cartilage
mTOR
post-traumatic osteoarthritis
Online Access:https://www.mdpi.com/2076-3921/10/1/8

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