A Robust and Sensitive Spectrophotometric Assay for the Enzymatic Activity of Bacterial Adenylate Cyclase Toxins

Various bacterial pathogens are producing toxins that target the cyclic Nucleotide Monophosphate (cNMPs) signaling pathways in order to facilitate host colonization. Among them, several are exhibiting potent nucleotidyl cyclase activities that are activated by eukaryotic factors, such as the adenyla...

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Bibliographic Details
Main Authors: Marilyne Davi, Mirko Sadi, Irene Pitard, Alexandre Chenal, Daniel Ladant
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/14/10/691