Syk/BLNK/NF-κB signaling promotes pancreatic injury induced by tacrolimus and potential protective effect from rapamycin

Syk/BLNK/NF-κB signaling promotes pancreatic injury induced by tacrolimus and potential protective effect from rapamycin

Background: The treatment of tacrolimus-induced post-transplantation diabetes mellitus (PTDM) has become a hot topic to improve the long-term survival of organ transplant patients, however whose pathogenesis has not been fully elucidated. In pancreas, the up-regulation of NF-κB has been reported to...

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Bibliographic Details
Main Authors: Xiao Chen, Ke Hu, Hao-Zhe Shi, Yi-Jia Zhang, Liang Chen, Su-Mei He, Dong-Dong Wang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Syk/BLNK/NF-κB signaling
Pancreatic injury
Tacrolimus
Potential protective
Rapamycin
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224000064

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