A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer.

A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer.

Cancer stem cells drive tumor growth and survival via self-renewal and therapeutic resistance, but the upstream mechanisms are not well defined. In this issue of PLOS Biology, a study in colon cancer reveals a new signalling network that links epigenetic regulation to these phenotypes.

Bibliographic Details
Main Authors:	Christopher G Hubert, Shaun R Stauffer, Justin D Lathia
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2023-09-01
Series:	PLoS Biology
Online Access:	https://doi.org/10.1371/journal.pbio.3002295

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