Detection of Hepatocellular Carcinoma in a High-Risk Population by a Mass Spectrometry-Based Test

Detection of Hepatocellular Carcinoma in a High-Risk Population by a Mass Spectrometry-Based Test

Hepatocellular carcinoma (HCC) is one of the fastest growing causes of cancer-related death. Guidelines recommend obtaining a screening ultrasound with or without alpha-fetoprotein (AFP) every 6 months in at-risk adults. AFP as a screening biomarker is plagued by low sensitivity/specificity, prompti...

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Bibliographic Details
Main Authors: Devalingam Mahalingam, Leonidas Chelis, Imran Nizamuddin, Sunyoung S. Lee, Stylianos Kakolyris, Glenn Halff, Ken Washburn, Kristopher Attwood, Ibnshamsah Fahad, Julia Grigorieva, Senait Asmellash, Krista Meyer, Carlos Oliveira, Heinrich Roder, Joanna Roder, Renuka Iyer
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
cancer screening
cirrhosis
AFP
machine learning
MALDI-TOF
proteomics
Online Access:https://www.mdpi.com/2072-6694/13/13/3109

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