Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysis

Summary: Background: The effect of different music interventions on depression in older adults is varied. We aimed to explore the comparative effect of different music intervention features on depression in older adults. Methods: We searched PubMed, EMBASE, CENTRAL, CINAHL, and ProQuest Dissertatio...

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Main Authors: Teerapon Dhippayom, Thitinan Saensook, Natthamon Promkhatja, Thanasak Teaktong, Nathorn Chaiyakunapruk, Beth Devine
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:EClinicalMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537022002395
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author Teerapon Dhippayom
Thitinan Saensook
Natthamon Promkhatja
Thanasak Teaktong
Nathorn Chaiyakunapruk
Beth Devine
author_facet Teerapon Dhippayom
Thitinan Saensook
Natthamon Promkhatja
Thanasak Teaktong
Nathorn Chaiyakunapruk
Beth Devine
author_sort Teerapon Dhippayom
collection DOAJ
description Summary: Background: The effect of different music interventions on depression in older adults is varied. We aimed to explore the comparative effect of different music intervention features on depression in older adults. Methods: We searched PubMed, EMBASE, CENTRAL, CINAHL, and ProQuest Dissertations&Theses from inception to October 2021 for randomized controlled trials (RCTs) of music interventions in participants aged ≥60 years. Music interventions were classified based on the TIP (theme, intensity, and provider/platform) framework. The theme was divided into: 1) active music therapy (ACT); 2) receptive music therapy (Recep); and 3) music medicine (MM). The intensity was classified as high (>60 minutes/week), and low (≤60 minutes/week). The provider was classified as a music therapist (MT) or a non-music therapist (NonMT). Summary standardized mean differences (SMD) of level of depression with 95% confidence interval (CI) were estimated using a frequentist framework with a random-effects model. The certainty of evidence was evaluated using the Confidence in Network Meta-Analysis (CINeMA) approach. This study was registered with PROSPERO (CRD42021247165). Findings: Fifteen RCTs involving 1,144 older adults (mean age 67.9-86.6 years) were included. When compared with usual care, the most effective music intervention was active music therapy >60 minutes/week by music therapist (Act/High/MT) (SMD -3.00; 95%CI, -3.64,-2.35), followed by music medicine >60 minutes/week by non-music therapist (MM/High/NonMT) (SMD -2.06; 95%CI, -2.78,-1.35) with moderate and high certainty of evidence, respectively. Depression scores in older adults treated with ACT/High/MT was also significantly lower than all other interventions, except MM/High/NonMT. Low intensity music interventions other than Act/Low/MT had no impact on depression. Interpretation: Although active music therapy >60 minutes/week by music therapist is the most effective intervention to alleviate depression in older adults, music medicine by listening to music of older adult's own preference >60 minutes/week is an alternative approach in settings with limited resources. Funding: None.
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spelling doaj.art-3c799591d3da4e47bf2edbcde04af0a72022-12-22T02:41:27ZengElsevierEClinicalMedicine2589-53702022-08-0150101509Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysisTeerapon Dhippayom0Thitinan Saensook1Natthamon Promkhatja2Thanasak Teaktong3Nathorn Chaiyakunapruk4Beth Devine5The Research Unit of Evidence Synthesis (TRUES), Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; Corresponding author at: The Research Unit of Evidence Synthesis (TRUES), Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, ThailandFaculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, ThailandFaculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, ThailandDepartment of Pharmacotherapy, University of Utah College of Pharmacy; IDEAS Center, Veterans Affairs Salt Lake City Healthcare System, Salt Lake City, UT, USAThe Comparative Health Outcomes, Policy, and Economics (CHOICE) Institute; School of Pharmacy; University of WashingtonSummary: Background: The effect of different music interventions on depression in older adults is varied. We aimed to explore the comparative effect of different music intervention features on depression in older adults. Methods: We searched PubMed, EMBASE, CENTRAL, CINAHL, and ProQuest Dissertations&Theses from inception to October 2021 for randomized controlled trials (RCTs) of music interventions in participants aged ≥60 years. Music interventions were classified based on the TIP (theme, intensity, and provider/platform) framework. The theme was divided into: 1) active music therapy (ACT); 2) receptive music therapy (Recep); and 3) music medicine (MM). The intensity was classified as high (>60 minutes/week), and low (≤60 minutes/week). The provider was classified as a music therapist (MT) or a non-music therapist (NonMT). Summary standardized mean differences (SMD) of level of depression with 95% confidence interval (CI) were estimated using a frequentist framework with a random-effects model. The certainty of evidence was evaluated using the Confidence in Network Meta-Analysis (CINeMA) approach. This study was registered with PROSPERO (CRD42021247165). Findings: Fifteen RCTs involving 1,144 older adults (mean age 67.9-86.6 years) were included. When compared with usual care, the most effective music intervention was active music therapy >60 minutes/week by music therapist (Act/High/MT) (SMD -3.00; 95%CI, -3.64,-2.35), followed by music medicine >60 minutes/week by non-music therapist (MM/High/NonMT) (SMD -2.06; 95%CI, -2.78,-1.35) with moderate and high certainty of evidence, respectively. Depression scores in older adults treated with ACT/High/MT was also significantly lower than all other interventions, except MM/High/NonMT. Low intensity music interventions other than Act/Low/MT had no impact on depression. Interpretation: Although active music therapy >60 minutes/week by music therapist is the most effective intervention to alleviate depression in older adults, music medicine by listening to music of older adult's own preference >60 minutes/week is an alternative approach in settings with limited resources. Funding: None.http://www.sciencedirect.com/science/article/pii/S2589537022002395Music interventionMusic therapyMusic medicineMusic listeningDepressionOlder adults
spellingShingle Teerapon Dhippayom
Thitinan Saensook
Natthamon Promkhatja
Thanasak Teaktong
Nathorn Chaiyakunapruk
Beth Devine
Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysis
EClinicalMedicine
Music intervention
Music therapy
Music medicine
Music listening
Depression
Older adults
title Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysis
title_full Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysis
title_fullStr Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysis
title_full_unstemmed Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysis
title_short Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysis
title_sort comparative effects of music interventions on depression in older adults a systematic review and network meta analysis
topic Music intervention
Music therapy
Music medicine
Music listening
Depression
Older adults
url http://www.sciencedirect.com/science/article/pii/S2589537022002395
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