Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients

Intensity modulated radiotherapy (IMRT) has become widely used as a standard radiation therapy technique for the treatment of localized prostate cancer. The transition from conformal radiotherapy (3D CRT) to a more complex IMRT technique triggered the need for more thorough verification of the ac...

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Main Authors: Iva Mrčela, Marin Gregov, Ante Matanić, Mirjana Budanec, Jure Murgić, Blanka Jakšić, Marin Prpić, Angela Prgomet Sečan, Ana Fröbe
Format: Article
Language:English
Published: Sestre Milosrdnice University hospital, Institute of Clinical Medical Research 2022-01-01
Series:Acta Clinica Croatica
Subjects:
Online Access:https://hrcak.srce.hr/file/414236
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author Iva Mrčela
Marin Gregov
Ante Matanić
Mirjana Budanec
Jure Murgić
Blanka Jakšić
Marin Prpić
Angela Prgomet Sečan
Ana Fröbe
author_facet Iva Mrčela
Marin Gregov
Ante Matanić
Mirjana Budanec
Jure Murgić
Blanka Jakšić
Marin Prpić
Angela Prgomet Sečan
Ana Fröbe
author_sort Iva Mrčela
collection DOAJ
description Intensity modulated radiotherapy (IMRT) has become widely used as a standard radiation therapy technique for the treatment of localized prostate cancer. The transition from conformal radiotherapy (3D CRT) to a more complex IMRT technique triggered the need for more thorough verification of the accuracy in the dose delivery. In this work we present the clinical workflow and the results of patient specific quality assurance (PSQA) procedures for 40 prostate cancer patients who have been treated with step and shot IMRT ever since its implementation in our routine clinical practice. PSQA procedures include dosimetric verification of each treatment plan with dedicated rotational phantom and high-resolution matrix detector system Octavius 4D (PTW Freiburg) that allows three-dimensional comparison of the calculated and delivered radiation dose distribution. Our results proved the compliance with the universal tolerance limits recommended for those procedures (1), assuring the safety of the treatment and providing the possibility for the adoption of more stringent constraints in the future.
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spelling doaj.art-3c7dc1bdc1b347e5ae331de59cbb7aa52024-04-15T18:03:34ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512022-01-0161.Supplement 3212710.20471/acc.2022.61.s3.3Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer PatientsIva Mrčela0Marin Gregov1Ante Matanić2Mirjana Budanec3Jure Murgić4Blanka Jakšić5Marin Prpić6Angela Prgomet Sečan7Ana Fröbe8Department of Medical Physics; University of Applied Health Sciences, Zagreb, CroatiaDepartment of Medical Physics; University of Applied Health Sciences, Zagreb, CroatiaDepartment of Medical Physics; University of Applied Health Sciences, Zagreb, CroatiaDepartment of Medical Physics; University of Applied Health Sciences, Zagreb, CroatiaDepartement of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; University of Applied Health Sciences, Zagreb, CroatiaDepartement of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb; CroatiaDepartement of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, CroatiaDepartement of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaDepartement of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, CroatiaIntensity modulated radiotherapy (IMRT) has become widely used as a standard radiation therapy technique for the treatment of localized prostate cancer. The transition from conformal radiotherapy (3D CRT) to a more complex IMRT technique triggered the need for more thorough verification of the accuracy in the dose delivery. In this work we present the clinical workflow and the results of patient specific quality assurance (PSQA) procedures for 40 prostate cancer patients who have been treated with step and shot IMRT ever since its implementation in our routine clinical practice. PSQA procedures include dosimetric verification of each treatment plan with dedicated rotational phantom and high-resolution matrix detector system Octavius 4D (PTW Freiburg) that allows three-dimensional comparison of the calculated and delivered radiation dose distribution. Our results proved the compliance with the universal tolerance limits recommended for those procedures (1), assuring the safety of the treatment and providing the possibility for the adoption of more stringent constraints in the future.https://hrcak.srce.hr/file/414236Prostate IMRTPatient Specific QA
spellingShingle Iva Mrčela
Marin Gregov
Ante Matanić
Mirjana Budanec
Jure Murgić
Blanka Jakšić
Marin Prpić
Angela Prgomet Sečan
Ana Fröbe
Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients
Acta Clinica Croatica
Prostate IMRT
Patient Specific QA
title Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients
title_full Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients
title_fullStr Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients
title_full_unstemmed Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients
title_short Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients
title_sort dosimetric verification of intensity modulated radiotherapy imrt treatment plans for prostate cancer patients
topic Prostate IMRT
Patient Specific QA
url https://hrcak.srce.hr/file/414236
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