A comparison of imaging modalities for the diagnosis of osteomyelitis
Osteomyelitis is an increasingly common pathology that often poses a diagnostic challenge to clinicians. Accurate and timely diagnosis is critical to preventing complications that can result in the loss of life or limb. In addition to history, physical exam, and laboratory studies, diagnostic imagin...
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| Format: | Article |
| Language: | English |
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Marshall University
2016-07-01
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| Series: | Marshall Journal of Medicine |
| Subjects: | |
| Online Access: | https://mds.marshall.edu/cgi/viewcontent.cgi?article=1044&context=mjm |
| _version_ | 1828888317012213760 |
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| author | Brandon J. Smith Grant S. Buchanan Franklin D. Shuler |
| author_facet | Brandon J. Smith Grant S. Buchanan Franklin D. Shuler |
| author_sort | Brandon J. Smith |
| collection | DOAJ |
| description | Osteomyelitis is an increasingly common pathology that often poses a diagnostic challenge to clinicians. Accurate and timely diagnosis is critical to preventing complications that can result in the loss of life or limb. In addition to history, physical exam, and laboratory studies, diagnostic imaging plays an essential role in the diagnostic process. This narrative review article discusses various imaging modalities employed to diagnose osteomyelitis: plain films, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, bone scintigraphy, and positron emission tomography (PET). Articles were obtained from Pubmed and screened for relevance to the topic of diagnostic imaging for osteomyelitis. The authors conclude that plain films are an appropriate first step, as they may reveal osteolytic changes and can help rule out alternative pathology. MRI is often the most appropriate second study, as it is highly sensitive and can detect bone marrow changes within days of an infection. Other studies such as CT, ultrasound, and bone scintigraphy may be useful in patients who cannot undergo MRI. CT is useful for identifying necrotic bone in chronic infections. Ultrasound may be useful in children or those with sickle-cell disease. Bone scintigraphy is particularly useful for vertebral osteomyelitis. Finally, PET scan has demonstrated high sensitivity and specificity; however, its clinical application is limited by its high cost and poor availability. When used appropriately, diagnostic imaging can provide high sensitivity and specificity for detecting osteomyelitis, making radiographic evaluation a crucial step in the diagnostic process of this debilitating condition. |
| first_indexed | 2024-12-13T12:20:32Z |
| format | Article |
| id | doaj.art-3c7f12298f3040ce92d613ed871a4e99 |
| institution | Directory Open Access Journal |
| issn | 2379-9536 |
| language | English |
| last_indexed | 2024-12-13T12:20:32Z |
| publishDate | 2016-07-01 |
| publisher | Marshall University |
| record_format | Article |
| series | Marshall Journal of Medicine |
| spelling | doaj.art-3c7f12298f3040ce92d613ed871a4e992022-12-21T23:46:35ZengMarshall UniversityMarshall Journal of Medicine2379-95362016-07-01238392http://dx.doi.org/10.18590/mjm.2016.vol2.iss3.10A comparison of imaging modalities for the diagnosis of osteomyelitisBrandon J. Smith0Grant S. Buchanan1 Franklin D. Shuler2Marshall University Joan C. Edwards School of MedicineMarshall UniversityMarshall UniversityOsteomyelitis is an increasingly common pathology that often poses a diagnostic challenge to clinicians. Accurate and timely diagnosis is critical to preventing complications that can result in the loss of life or limb. In addition to history, physical exam, and laboratory studies, diagnostic imaging plays an essential role in the diagnostic process. This narrative review article discusses various imaging modalities employed to diagnose osteomyelitis: plain films, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, bone scintigraphy, and positron emission tomography (PET). Articles were obtained from Pubmed and screened for relevance to the topic of diagnostic imaging for osteomyelitis. The authors conclude that plain films are an appropriate first step, as they may reveal osteolytic changes and can help rule out alternative pathology. MRI is often the most appropriate second study, as it is highly sensitive and can detect bone marrow changes within days of an infection. Other studies such as CT, ultrasound, and bone scintigraphy may be useful in patients who cannot undergo MRI. CT is useful for identifying necrotic bone in chronic infections. Ultrasound may be useful in children or those with sickle-cell disease. Bone scintigraphy is particularly useful for vertebral osteomyelitis. Finally, PET scan has demonstrated high sensitivity and specificity; however, its clinical application is limited by its high cost and poor availability. When used appropriately, diagnostic imaging can provide high sensitivity and specificity for detecting osteomyelitis, making radiographic evaluation a crucial step in the diagnostic process of this debilitating condition.https://mds.marshall.edu/cgi/viewcontent.cgi?article=1044&context=mjmDiagnostic ImagingOsteomyelitisRadiologyX-rayCTMRIBone ScanUltrasound |
| spellingShingle | Brandon J. Smith Grant S. Buchanan Franklin D. Shuler A comparison of imaging modalities for the diagnosis of osteomyelitis Marshall Journal of Medicine Diagnostic Imaging Osteomyelitis Radiology X-ray CT MRI Bone Scan Ultrasound |
| title | A comparison of imaging modalities for the diagnosis of osteomyelitis |
| title_full | A comparison of imaging modalities for the diagnosis of osteomyelitis |
| title_fullStr | A comparison of imaging modalities for the diagnosis of osteomyelitis |
| title_full_unstemmed | A comparison of imaging modalities for the diagnosis of osteomyelitis |
| title_short | A comparison of imaging modalities for the diagnosis of osteomyelitis |
| title_sort | comparison of imaging modalities for the diagnosis of osteomyelitis |
| topic | Diagnostic Imaging Osteomyelitis Radiology X-ray CT MRI Bone Scan Ultrasound |
| url | https://mds.marshall.edu/cgi/viewcontent.cgi?article=1044&context=mjm |
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