A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures

A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures

Transmissible spongiform encephalopathies (TSEs) are a group of invariably fatal neurodegenerative disorders. The causal agent is an aberrantly folded isoform (PrPSc or prion) of the endogenous prion protein (PrPC) which is neurotoxic and amyloidogenic and induces misfolding of its physiological cou...

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Bibliographic Details
Main Authors:	Hasier Eraña, Miguel Ángel Pérez-Castro, Sandra García-Martínez, Jorge M. Charco, Rafael López-Moreno, Carlos M. Díaz-Dominguez, Tomás Barrio, Ezequiel González-Miranda, Joaquín Castilla
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-10-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	transmissible spongiform encephalopathy prion decontamination PMSA in vitro propagation
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2020.589182/full

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