Network-wide effects of pallidal deep brain stimulation normalised abnormal cerebellar cortical activity in the dystonic animal model

Network-wide effects of pallidal deep brain stimulation normalised abnormal cerebellar cortical activity in the dystonic animal model

Background: Deep brain stimulation (DBS) targeting globus pallidus internus (GPi) is a recognised therapy for drug-refractory dystonia. However, the mechanisms underlying this effect are not fully understood. This study explores how pallidal DBS alters spatiotemporal pattern formation of neuronal dy...

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Detalhes bibliográficos
Main Authors: Fabiana Santana Kragelund, Konstantinos Spiliotis, Marco Heerdegen, Tina Sellmann, Henning Bathel, Anika Lüttig, Angelika Richter, Jens Starke, Rüdiger Köhling, Denise Franz
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2025-02-01
Colecção:Neurobiology of Disease
Assuntos:
Cerebellar network activity
pallidal deep brain stimulation
generalised dystonia
high-density microelectrode arrays
dtsz mutant hamster
spatiotemporal analysis
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996124003814

Internet

http://www.sciencedirect.com/science/article/pii/S0969996124003814

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