A new approach in acute myeloid leukemia (AML): Samatya-predicting score
We aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the “Samatya-predicting score”. A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determ...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Leukemia Research Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221304892200005X |
| _version_ | 1811324054082158592 |
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| author | Istemi Serin Bagnu Orhan Derya Sonmez Tahir Alper Cinli Hasan Goze Huriye Serin Begum Gulesir Osman Yokus |
| author_facet | Istemi Serin Bagnu Orhan Derya Sonmez Tahir Alper Cinli Hasan Goze Huriye Serin Begum Gulesir Osman Yokus |
| author_sort | Istemi Serin |
| collection | DOAJ |
| description | We aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the “Samatya-predicting score”. A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determined as 2,5. The sensitivity for mortality was 88% and the specificity was 42%. In terms of being non-responder to induction therapy, the sensitivity was 90,1%, the specificity was 25,3%. OS was shorter in those with high risk scores. This study makes an important contribution to the literature in terms of creating a different perspective to predict prognosis in AML. |
| first_indexed | 2024-04-13T14:06:18Z |
| format | Article |
| id | doaj.art-3c87bb9d613745b8bfd70c5f009965eb |
| institution | Directory Open Access Journal |
| issn | 2213-0489 |
| language | English |
| last_indexed | 2024-04-13T14:06:18Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Leukemia Research Reports |
| spelling | doaj.art-3c87bb9d613745b8bfd70c5f009965eb2022-12-22T02:43:53ZengElsevierLeukemia Research Reports2213-04892022-01-0117100293A new approach in acute myeloid leukemia (AML): Samatya-predicting scoreIstemi Serin0Bagnu Orhan1Derya Sonmez2Tahir Alper Cinli3Hasan Goze4Huriye Serin5Begum Gulesir6Osman Yokus7Department of Hematology, University of Health Sciences, Istanbul Training and Research Hospital, Org. Nafiz GURMAN Cad., Samatya, Fatih, Istanbul, Istanbul, 34098 Turkey; Corresponding author.Department of Medical Biochemistry, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, TurkeyDepartment of Medical Biochemistry, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, TurkeyDepartment of Hematology, University of Health Sciences, Istanbul Training and Research Hospital, Org. Nafiz GURMAN Cad., Samatya, Fatih, Istanbul, Istanbul, 34098 TurkeyDepartment of Hematology, University of Health Sciences, Istanbul Training and Research Hospital, Org. Nafiz GURMAN Cad., Samatya, Fatih, Istanbul, Istanbul, 34098 TurkeyDepartment of Medical Biochemistry, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, TurkeyDepartment of Internal Medicine, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul, TurkeyDepartment of Hematology, University of Health Sciences, Istanbul Training and Research Hospital, Org. Nafiz GURMAN Cad., Samatya, Fatih, Istanbul, Istanbul, 34098 TurkeyWe aimed to examine the efficiency for prediction of prognosis and response in non-APL AML cases of the “Samatya-predicting score”. A total of 213 patients diagnosed between January 2010-December 2020 were examined. Of the 158 patients included in the study, the median value of risk score was determined as 2,5. The sensitivity for mortality was 88% and the specificity was 42%. In terms of being non-responder to induction therapy, the sensitivity was 90,1%, the specificity was 25,3%. OS was shorter in those with high risk scores. This study makes an important contribution to the literature in terms of creating a different perspective to predict prognosis in AML.http://www.sciencedirect.com/science/article/pii/S221304892200005XAcute myeloid leukemiaFlow cytometryResponsePrognosis |
| spellingShingle | Istemi Serin Bagnu Orhan Derya Sonmez Tahir Alper Cinli Hasan Goze Huriye Serin Begum Gulesir Osman Yokus A new approach in acute myeloid leukemia (AML): Samatya-predicting score Leukemia Research Reports Acute myeloid leukemia Flow cytometry Response Prognosis |
| title | A new approach in acute myeloid leukemia (AML): Samatya-predicting score |
| title_full | A new approach in acute myeloid leukemia (AML): Samatya-predicting score |
| title_fullStr | A new approach in acute myeloid leukemia (AML): Samatya-predicting score |
| title_full_unstemmed | A new approach in acute myeloid leukemia (AML): Samatya-predicting score |
| title_short | A new approach in acute myeloid leukemia (AML): Samatya-predicting score |
| title_sort | new approach in acute myeloid leukemia aml samatya predicting score |
| topic | Acute myeloid leukemia Flow cytometry Response Prognosis |
| url | http://www.sciencedirect.com/science/article/pii/S221304892200005X |
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