Non-additive Effects in Genomic Selection
In the last decade, genomic selection has become a standard in the genetic evaluation of livestock populations. However, most procedures for the implementation of genomic selection only consider the additive effects associated with SNP (Single Nucleotide Polymorphism) markers used to calculate the p...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-03-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fgene.2018.00078/full |
| _version_ | 1811342701828767744 |
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| author | Luis Varona Luis Varona Andres Legarra Miguel A. Toro Zulma G. Vitezica |
| author_facet | Luis Varona Luis Varona Andres Legarra Miguel A. Toro Zulma G. Vitezica |
| author_sort | Luis Varona |
| collection | DOAJ |
| description | In the last decade, genomic selection has become a standard in the genetic evaluation of livestock populations. However, most procedures for the implementation of genomic selection only consider the additive effects associated with SNP (Single Nucleotide Polymorphism) markers used to calculate the prediction of the breeding values of candidates for selection. Nevertheless, the availability of estimates of non-additive effects is of interest because: (i) they contribute to an increase in the accuracy of the prediction of breeding values and the genetic response; (ii) they allow the definition of mate allocation procedures between candidates for selection; and (iii) they can be used to enhance non-additive genetic variation through the definition of appropriate crossbreeding or purebred breeding schemes. This study presents a review of methods for the incorporation of non-additive genetic effects into genomic selection procedures and their potential applications in the prediction of future performance, mate allocation, crossbreeding, and purebred selection. The work concludes with a brief outline of some ideas for future lines of that may help the standard inclusion of non-additive effects in genomic selection. |
| first_indexed | 2024-04-13T19:15:30Z |
| format | Article |
| id | doaj.art-3c8a434cd89143bf9c32b7393a25c96b |
| institution | Directory Open Access Journal |
| issn | 1664-8021 |
| language | English |
| last_indexed | 2024-04-13T19:15:30Z |
| publishDate | 2018-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Genetics |
| spelling | doaj.art-3c8a434cd89143bf9c32b7393a25c96b2022-12-22T02:33:41ZengFrontiers Media S.A.Frontiers in Genetics1664-80212018-03-01910.3389/fgene.2018.00078341678Non-additive Effects in Genomic SelectionLuis Varona0Luis Varona1Andres Legarra2Miguel A. Toro3Zulma G. Vitezica4Departamento de Anatomía, Embriología y Genética Animal, Universidad de Zaragoza, Zaragoza, SpainInstituto Agroalimentario de Aragón (IA2), Zaragoza, SpainGénétique Physiologie et Systèmes d'Elevage (GenPhySE), Institut National de la Recherche Agronomique de Toulouse, Castanet-Tolosan, FranceDepartamento Producción Agraria, ETS Ingeniería Agronómica, Alimentaria y de Biosistemas, Universidad Politécnica de Madrid, Madrid, SpainGénétique Physiologie et Systèmes d'Elevage (GenPhySE), Université de Toulouse, Castanet-Tolosan, FranceIn the last decade, genomic selection has become a standard in the genetic evaluation of livestock populations. However, most procedures for the implementation of genomic selection only consider the additive effects associated with SNP (Single Nucleotide Polymorphism) markers used to calculate the prediction of the breeding values of candidates for selection. Nevertheless, the availability of estimates of non-additive effects is of interest because: (i) they contribute to an increase in the accuracy of the prediction of breeding values and the genetic response; (ii) they allow the definition of mate allocation procedures between candidates for selection; and (iii) they can be used to enhance non-additive genetic variation through the definition of appropriate crossbreeding or purebred breeding schemes. This study presents a review of methods for the incorporation of non-additive genetic effects into genomic selection procedures and their potential applications in the prediction of future performance, mate allocation, crossbreeding, and purebred selection. The work concludes with a brief outline of some ideas for future lines of that may help the standard inclusion of non-additive effects in genomic selection.http://journal.frontiersin.org/article/10.3389/fgene.2018.00078/fullgenomic selectiondominanceepistasiscrossbreedinggenetic evaluation |
| spellingShingle | Luis Varona Luis Varona Andres Legarra Miguel A. Toro Zulma G. Vitezica Non-additive Effects in Genomic Selection Frontiers in Genetics genomic selection dominance epistasis crossbreeding genetic evaluation |
| title | Non-additive Effects in Genomic Selection |
| title_full | Non-additive Effects in Genomic Selection |
| title_fullStr | Non-additive Effects in Genomic Selection |
| title_full_unstemmed | Non-additive Effects in Genomic Selection |
| title_short | Non-additive Effects in Genomic Selection |
| title_sort | non additive effects in genomic selection |
| topic | genomic selection dominance epistasis crossbreeding genetic evaluation |
| url | http://journal.frontiersin.org/article/10.3389/fgene.2018.00078/full |
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