From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube

From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube

Liquid biopsies hold great promise for the management of cancer. Reliable liquid biopsy data depend on stable and reproducible pre-analytical protocols that comply with quality measures, irrespective of the sampling and processing site. We established a workflow for plasma preservation, followed by...

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Bibliographic Details
Main Authors: Kendra K. Maass, Paulina S. Schad, Agnes M. E. Finster, Pitithat Puranachot, Fabian Rosing, Tatjana Wedig, Nathalie Schwarz, Natalie Stumpf, Stefan M. Pfister, Kristian W. Pajtler
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
liquid biopsy
cell-free DNA
cell-free RNA
blood preservation tubes
CSF
size selection
Online Access:https://www.mdpi.com/2072-6694/13/12/3002

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