Epithelial Ovarian Cancer—Varied Treatment Results
Ovarian cancer (OC) is the eighth most common cancer worldwide and is usually diagnosed in advanced stages. Despite many available data, no treatment results have been reviewed in Poland. This study enrolled 289 first-time patients treated between 2018 and 2021 by the Department of Oncology of the P...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-07-01
|
| Series: | Healthcare |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9032/11/14/2043 |
| _version_ | 1797589096268300288 |
|---|---|
| author | Sonja Millert-Kalińska Marcin Przybylski Dominik Pruski Małgorzata Stawicka-Niełacna Radosław Mądry |
| author_facet | Sonja Millert-Kalińska Marcin Przybylski Dominik Pruski Małgorzata Stawicka-Niełacna Radosław Mądry |
| author_sort | Sonja Millert-Kalińska |
| collection | DOAJ |
| description | Ovarian cancer (OC) is the eighth most common cancer worldwide and is usually diagnosed in advanced stages. Despite many available data, no treatment results have been reviewed in Poland. This study enrolled 289 first-time patients treated between 2018 and 2021 by the Department of Oncology of the Poznań University of Medical Sciences (SKPP). The relationships among starting treatment in our centre, the type of first intervention, and the final decision were significant (<i>p</i> < 0.001). Patients in the SKPP group were more likely to primarily have a laparoscopy and less likely to have an exploratory laparotomy. Neoadjuvant chemotherapy (NACT) after a laparotomy was less often a final decision among SKPP patients (9% vs. 22%), in contrary to NACT after a laparoscopy (23% vs. 4%). Factors affecting the shortening of progression-free survival (PFS) were an advanced stage of the disease, a histopathological diagnosis, the type of cytoreduction, and the final decision. Significance according to the final decision was revealed for PDS vs. NACT after a laparotomy (<i>p</i> < 0.001) and for PDS vs. NACT after a laparoscopy (<i>p</i> = 0.011). Our study supports the benefits of treating ovarian cancer in an oncology centre with a high patient throughput. Further observations might also answer the question about overall survival (OS). |
| first_indexed | 2024-03-11T01:01:28Z |
| format | Article |
| id | doaj.art-3c91488c9ed64dc29172a768efe4fd66 |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-11T01:01:28Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-3c91488c9ed64dc29172a768efe4fd662023-11-18T19:33:09ZengMDPI AGHealthcare2227-90322023-07-011114204310.3390/healthcare11142043Epithelial Ovarian Cancer—Varied Treatment ResultsSonja Millert-Kalińska0Marcin Przybylski1Dominik Pruski2Małgorzata Stawicka-Niełacna3Radosław Mądry4Doctoral School, Poznan University of Medical Sciences, 61-701 Poznań, PolandDepartment of Obstetrics and Gynecology, District Public Hospital in Poznan, 60-479 Poznań, PolandDepartment of Obstetrics and Gynecology, District Public Hospital in Poznan, 60-479 Poznań, PolandDepartment of Clinical Genetics and Pathology, University of Zielona Góra, 65-046 Zielona Góra, PolandDepartment of Oncology, Poznan University of Medical Sciences, 60-569 Poznań, PolandOvarian cancer (OC) is the eighth most common cancer worldwide and is usually diagnosed in advanced stages. Despite many available data, no treatment results have been reviewed in Poland. This study enrolled 289 first-time patients treated between 2018 and 2021 by the Department of Oncology of the Poznań University of Medical Sciences (SKPP). The relationships among starting treatment in our centre, the type of first intervention, and the final decision were significant (<i>p</i> < 0.001). Patients in the SKPP group were more likely to primarily have a laparoscopy and less likely to have an exploratory laparotomy. Neoadjuvant chemotherapy (NACT) after a laparotomy was less often a final decision among SKPP patients (9% vs. 22%), in contrary to NACT after a laparoscopy (23% vs. 4%). Factors affecting the shortening of progression-free survival (PFS) were an advanced stage of the disease, a histopathological diagnosis, the type of cytoreduction, and the final decision. Significance according to the final decision was revealed for PDS vs. NACT after a laparotomy (<i>p</i> < 0.001) and for PDS vs. NACT after a laparoscopy (<i>p</i> = 0.011). Our study supports the benefits of treating ovarian cancer in an oncology centre with a high patient throughput. Further observations might also answer the question about overall survival (OS).https://www.mdpi.com/2227-9032/11/14/2043epithelial ovarian cancerEOCdisparities in treatmentlaparoscopy in oncologycytoreduction |
| spellingShingle | Sonja Millert-Kalińska Marcin Przybylski Dominik Pruski Małgorzata Stawicka-Niełacna Radosław Mądry Epithelial Ovarian Cancer—Varied Treatment Results Healthcare epithelial ovarian cancer EOC disparities in treatment laparoscopy in oncology cytoreduction |
| title | Epithelial Ovarian Cancer—Varied Treatment Results |
| title_full | Epithelial Ovarian Cancer—Varied Treatment Results |
| title_fullStr | Epithelial Ovarian Cancer—Varied Treatment Results |
| title_full_unstemmed | Epithelial Ovarian Cancer—Varied Treatment Results |
| title_short | Epithelial Ovarian Cancer—Varied Treatment Results |
| title_sort | epithelial ovarian cancer varied treatment results |
| topic | epithelial ovarian cancer EOC disparities in treatment laparoscopy in oncology cytoreduction |
| url | https://www.mdpi.com/2227-9032/11/14/2043 |
| work_keys_str_mv | AT sonjamillertkalinska epithelialovariancancervariedtreatmentresults AT marcinprzybylski epithelialovariancancervariedtreatmentresults AT dominikpruski epithelialovariancancervariedtreatmentresults AT małgorzatastawickaniełacna epithelialovariancancervariedtreatmentresults AT radosławmadry epithelialovariancancervariedtreatmentresults |