Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting

Abstract Days alive and out of hospital (DAOH) is a simple estimator based on the number of days not in hospital within a defined period. In cases of mortality within the period, DAOH is regarded as zero. It has not been validated solely in off-pump coronary artery bypass grafting (OPCAB). This stud...

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Main Authors: Ah Ran Oh, Seung-Hwa Lee, Jungchan Park, Jeong-Jin Min, Jong-Hwan Lee, Seung Yeon Yoo, Ji-Hye Kwon, Dan-Cheong Choi, Wooksung Kim, Hyun Sung Cho
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30321-8
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author Ah Ran Oh
Seung-Hwa Lee
Jungchan Park
Jeong-Jin Min
Jong-Hwan Lee
Seung Yeon Yoo
Ji-Hye Kwon
Dan-Cheong Choi
Wooksung Kim
Hyun Sung Cho
author_facet Ah Ran Oh
Seung-Hwa Lee
Jungchan Park
Jeong-Jin Min
Jong-Hwan Lee
Seung Yeon Yoo
Ji-Hye Kwon
Dan-Cheong Choi
Wooksung Kim
Hyun Sung Cho
author_sort Ah Ran Oh
collection DOAJ
description Abstract Days alive and out of hospital (DAOH) is a simple estimator based on the number of days not in hospital within a defined period. In cases of mortality within the period, DAOH is regarded as zero. It has not been validated solely in off-pump coronary artery bypass grafting (OPCAB). This study aimed to demonstrate a correlation between DAOH and outcome of OPCAB. We identified 2211 OPCAB performed from January 2010 to August 2016. We calculated DAOH at 30 and 60 days. We generated a receiver-operating curve and compared outcomes. The median duration of hospital stay after OPCAB was 6 days. The median DAOH values at 30 and 60 days were 24 and 54 days. The estimated thresholds for 3-year mortality for DAOH at 30 and 60 days were 20 and 50 days. Three-year mortality was higher for short DAOH (1.2% vs. 5.7% and 1.1% vs. 5.6% DAOH at 30 and 60 days). After adjustment, the short DAOH 30 group showed significantly higher mortality during 3-year follow-up (hazard ratio 3.07; 95% confidence interval 1.45–6.52; p = 0.004). DAOH at 30 days after OPCAB showed a correlation with 3-year outcomes. DAOH 30 might be a reliable long-term outcome measure that can be obtained within 30 days after surgery.
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spelling doaj.art-3c95a8a42316439db90128525a41a5fc2023-03-22T11:03:40ZengNature PortfolioScientific Reports2045-23222023-02-011311910.1038/s41598-023-30321-8Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass graftingAh Ran Oh0Seung-Hwa Lee1Jungchan Park2Jeong-Jin Min3Jong-Hwan Lee4Seung Yeon Yoo5Ji-Hye Kwon6Dan-Cheong Choi7Wooksung Kim8Hyun Sung Cho9Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineWiltse Memorial HospitalDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineAbstract Days alive and out of hospital (DAOH) is a simple estimator based on the number of days not in hospital within a defined period. In cases of mortality within the period, DAOH is regarded as zero. It has not been validated solely in off-pump coronary artery bypass grafting (OPCAB). This study aimed to demonstrate a correlation between DAOH and outcome of OPCAB. We identified 2211 OPCAB performed from January 2010 to August 2016. We calculated DAOH at 30 and 60 days. We generated a receiver-operating curve and compared outcomes. The median duration of hospital stay after OPCAB was 6 days. The median DAOH values at 30 and 60 days were 24 and 54 days. The estimated thresholds for 3-year mortality for DAOH at 30 and 60 days were 20 and 50 days. Three-year mortality was higher for short DAOH (1.2% vs. 5.7% and 1.1% vs. 5.6% DAOH at 30 and 60 days). After adjustment, the short DAOH 30 group showed significantly higher mortality during 3-year follow-up (hazard ratio 3.07; 95% confidence interval 1.45–6.52; p = 0.004). DAOH at 30 days after OPCAB showed a correlation with 3-year outcomes. DAOH 30 might be a reliable long-term outcome measure that can be obtained within 30 days after surgery.https://doi.org/10.1038/s41598-023-30321-8
spellingShingle Ah Ran Oh
Seung-Hwa Lee
Jungchan Park
Jeong-Jin Min
Jong-Hwan Lee
Seung Yeon Yoo
Ji-Hye Kwon
Dan-Cheong Choi
Wooksung Kim
Hyun Sung Cho
Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting
Scientific Reports
title Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting
title_full Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting
title_fullStr Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting
title_full_unstemmed Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting
title_short Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting
title_sort days alive and out of hospital at 30 days and outcomes of off pump coronary artery bypass grafting
url https://doi.org/10.1038/s41598-023-30321-8
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