Controlled Release of Volatile Antimicrobial Compounds from Mesoporous Silica Nanocarriers for Active Food Packaging Applications
Essential oils and their active components have been extensively reported in the literature for their efficient antimicrobial, antioxidant and antifungal properties. However, the sensitivity of these volatile compounds towards heat, oxygen and light limits their usage in real food packaging applicat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/13/7032 |
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| author | Tina Gulin-Sarfraz Georgios N. Kalantzopoulos John-Erik Haugen Lars Axelsson Hilde Raanaas Kolstad Jawad Sarfraz |
| author_facet | Tina Gulin-Sarfraz Georgios N. Kalantzopoulos John-Erik Haugen Lars Axelsson Hilde Raanaas Kolstad Jawad Sarfraz |
| author_sort | Tina Gulin-Sarfraz |
| collection | DOAJ |
| description | Essential oils and their active components have been extensively reported in the literature for their efficient antimicrobial, antioxidant and antifungal properties. However, the sensitivity of these volatile compounds towards heat, oxygen and light limits their usage in real food packaging applications. The encapsulation of these compounds into inorganic nanocarriers, such as nanoclays, has been shown to prolong the release and protect the compounds from harsh processing conditions. Nevertheless, these systems have limited shelf stability, and the release is of limited control. Thus, this study presents a mesoporous silica nanocarrier with a high surface area and well-ordered protective pore structure for loading large amounts of natural active compounds (up to 500 mg/g). The presented loaded nanocarriers are shelf-stable with a very slow initial release which levels out at 50% retention of the encapsulated compounds after 2 months. By the addition of simulated drip-loss from chicken, the release of the compounds is activated and gives an antimicrobial effect, which is demonstrated on the foodborne spoilage bacteria <i>Brochothrix</i><i>thermosphacta</i> and the potentially pathogenic bacteria <i>Escherichia coli</i>. When the release of the active compounds is activated, a ≥4-log reduction in the growth of <i>B. thermosphacta</i> and a 2-log reduction of <i>E. coli</i> is obtained, after only one hour of incubation. During the same one-hour incubation period the dry nanocarriers gave a negligible inhibitory effect. By using the proposed nanocarrier system, which is activated by the food product itself, increased availability of the natural antimicrobial compounds is expected, with a subsequent controlled antimicrobial effect. |
| first_indexed | 2024-03-09T21:50:42Z |
| format | Article |
| id | doaj.art-3c96a5e75c8c46eeb0ec5eb86a3e7ac8 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T21:50:42Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-3c96a5e75c8c46eeb0ec5eb86a3e7ac82023-11-23T20:06:46ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-06-012313703210.3390/ijms23137032Controlled Release of Volatile Antimicrobial Compounds from Mesoporous Silica Nanocarriers for Active Food Packaging ApplicationsTina Gulin-Sarfraz0Georgios N. Kalantzopoulos1John-Erik Haugen2Lars Axelsson3Hilde Raanaas Kolstad4Jawad Sarfraz5Nofima-Norwegian Institute of Food, Fisheries and Aquaculture Research, P.O. Box 210, NO-1431 Ås, NorwayCenter for Materials Science and Nanotechnology (SMN), Department of Chemistry, University of Oslo, P.O. Box 1033, Blindern, NO-0315 Oslo, NorwayNofima-Norwegian Institute of Food, Fisheries and Aquaculture Research, P.O. Box 210, NO-1431 Ås, NorwayNofima-Norwegian Institute of Food, Fisheries and Aquaculture Research, P.O. Box 210, NO-1431 Ås, NorwayImaging Centre, Faculty of Biosciences, Norwegian University of Life Sciences (NMBU), P.O. Box 5003, NO-1432 Ås, NorwayNofima-Norwegian Institute of Food, Fisheries and Aquaculture Research, P.O. Box 210, NO-1431 Ås, NorwayEssential oils and their active components have been extensively reported in the literature for their efficient antimicrobial, antioxidant and antifungal properties. However, the sensitivity of these volatile compounds towards heat, oxygen and light limits their usage in real food packaging applications. The encapsulation of these compounds into inorganic nanocarriers, such as nanoclays, has been shown to prolong the release and protect the compounds from harsh processing conditions. Nevertheless, these systems have limited shelf stability, and the release is of limited control. Thus, this study presents a mesoporous silica nanocarrier with a high surface area and well-ordered protective pore structure for loading large amounts of natural active compounds (up to 500 mg/g). The presented loaded nanocarriers are shelf-stable with a very slow initial release which levels out at 50% retention of the encapsulated compounds after 2 months. By the addition of simulated drip-loss from chicken, the release of the compounds is activated and gives an antimicrobial effect, which is demonstrated on the foodborne spoilage bacteria <i>Brochothrix</i><i>thermosphacta</i> and the potentially pathogenic bacteria <i>Escherichia coli</i>. When the release of the active compounds is activated, a ≥4-log reduction in the growth of <i>B. thermosphacta</i> and a 2-log reduction of <i>E. coli</i> is obtained, after only one hour of incubation. During the same one-hour incubation period the dry nanocarriers gave a negligible inhibitory effect. By using the proposed nanocarrier system, which is activated by the food product itself, increased availability of the natural antimicrobial compounds is expected, with a subsequent controlled antimicrobial effect.https://www.mdpi.com/1422-0067/23/13/7032mesoporous silica particlesnanocarriersencapsulationessential oil componentsstimulus activated releaseactive packaging |
| spellingShingle | Tina Gulin-Sarfraz Georgios N. Kalantzopoulos John-Erik Haugen Lars Axelsson Hilde Raanaas Kolstad Jawad Sarfraz Controlled Release of Volatile Antimicrobial Compounds from Mesoporous Silica Nanocarriers for Active Food Packaging Applications International Journal of Molecular Sciences mesoporous silica particles nanocarriers encapsulation essential oil components stimulus activated release active packaging |
| title | Controlled Release of Volatile Antimicrobial Compounds from Mesoporous Silica Nanocarriers for Active Food Packaging Applications |
| title_full | Controlled Release of Volatile Antimicrobial Compounds from Mesoporous Silica Nanocarriers for Active Food Packaging Applications |
| title_fullStr | Controlled Release of Volatile Antimicrobial Compounds from Mesoporous Silica Nanocarriers for Active Food Packaging Applications |
| title_full_unstemmed | Controlled Release of Volatile Antimicrobial Compounds from Mesoporous Silica Nanocarriers for Active Food Packaging Applications |
| title_short | Controlled Release of Volatile Antimicrobial Compounds from Mesoporous Silica Nanocarriers for Active Food Packaging Applications |
| title_sort | controlled release of volatile antimicrobial compounds from mesoporous silica nanocarriers for active food packaging applications |
| topic | mesoporous silica particles nanocarriers encapsulation essential oil components stimulus activated release active packaging |
| url | https://www.mdpi.com/1422-0067/23/13/7032 |
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