Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India
Introduction: Chronic Suppurative Otitis Media (CSOM) is a chronic and persistent inflammation of the mucosal lining of middle ear cleft which presents with recurrent ear discharge through a tympanic membrane perforation. CSOM is a worldwide disease and has higher prevalence in developing count...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2021-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/14770/48334_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf |
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| author | KIRAN YADAV SANDEEP KAUSHIK KUMKUM RANI ANUJ KUMAR TYAGI |
| author_facet | KIRAN YADAV SANDEEP KAUSHIK KUMKUM RANI ANUJ KUMAR TYAGI |
| author_sort | KIRAN YADAV |
| collection | DOAJ |
| description | Introduction: Chronic Suppurative Otitis Media (CSOM) is a
chronic and persistent inflammation of the mucosal lining of
middle ear cleft which presents with recurrent ear discharge
through a tympanic membrane perforation. CSOM is a
worldwide disease and has higher prevalence in developing
countries causing serious local damage and threatening
complications.
Aim: To determine the profile of CSOM, its causative agents
and their antibiotic susceptibility pattern.
Materials and Methods: The present study was a retrospective
study in which data for culture and antimicrobial susceptibility
profile of CSOM cases was retrieved from Microbiology
department of Government Medical College, Kannauj, Uttar
Pradesh, India, from January 2019 to October 2019 the analysis
of data was done in February 2020. Two hundred pus swabs from
discharging ears were processed during the study period for
aerobic bacterial culture and antimicrobial susceptibility pattern
in Microbiology department using standard microbiological
techniques. The result analysis of the study was expressed as
percentage and proportion for distribution of CSOM cases.
Results: Out of 200 patients, 114 (57%) were males and 86
(43%) females. Among the 200 cases, 147 (73.5%) cases
showed growth and 53 (26.5%) showed no growth. The most
common organism isolated in this study was Pseudomonas
aeruginosa, 67 (42.40%) followed by Staphylococcus aureus.
48 (30.37%) and Klebsiella spp. 23 (14.55%). Gentamicin (85%)
and amikacin (83%) had high level of antibacterial activity on all
the isolates. Meropenem was found to be most effective drug
for gram negative isolates. All Staphylococcus spp isolates
were sensitive to vancomycin (100%).
Conclusion: Pseudomonas aeruginosa was the most
predominant organism isolated in otitis media patients. Most of
the isolates were sensitive to meropenem. |
| first_indexed | 2024-12-21T16:16:24Z |
| format | Article |
| id | doaj.art-3c97afe5a2014fc88e1b30252864d646 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-21T16:16:24Z |
| publishDate | 2021-04-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-3c97afe5a2014fc88e1b30252864d6462022-12-21T18:57:41ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-04-01154DC05DC0810.7860/JCDR/2021/48334.14770Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, IndiaKIRAN YADAV0SANDEEP KAUSHIK1KUMKUM RANI2ANUJ KUMAR TYAGI3Assistant Professor, Department of Microbiology, Government Medical College, Kannauj, Uttar Pradesh, India.Professor, Department of Ent, Government Medical College, Kannauj, Uttar Pradesh, India.Demonstrator, Department of Microbiology, Government Medical College, Kannauj, Uttar Pradesh, India.Assistant Professor, Department of Microbiology, Government Medical College, Kannauj, Uttar Pradesh, India.Introduction: Chronic Suppurative Otitis Media (CSOM) is a chronic and persistent inflammation of the mucosal lining of middle ear cleft which presents with recurrent ear discharge through a tympanic membrane perforation. CSOM is a worldwide disease and has higher prevalence in developing countries causing serious local damage and threatening complications. Aim: To determine the profile of CSOM, its causative agents and their antibiotic susceptibility pattern. Materials and Methods: The present study was a retrospective study in which data for culture and antimicrobial susceptibility profile of CSOM cases was retrieved from Microbiology department of Government Medical College, Kannauj, Uttar Pradesh, India, from January 2019 to October 2019 the analysis of data was done in February 2020. Two hundred pus swabs from discharging ears were processed during the study period for aerobic bacterial culture and antimicrobial susceptibility pattern in Microbiology department using standard microbiological techniques. The result analysis of the study was expressed as percentage and proportion for distribution of CSOM cases. Results: Out of 200 patients, 114 (57%) were males and 86 (43%) females. Among the 200 cases, 147 (73.5%) cases showed growth and 53 (26.5%) showed no growth. The most common organism isolated in this study was Pseudomonas aeruginosa, 67 (42.40%) followed by Staphylococcus aureus. 48 (30.37%) and Klebsiella spp. 23 (14.55%). Gentamicin (85%) and amikacin (83%) had high level of antibacterial activity on all the isolates. Meropenem was found to be most effective drug for gram negative isolates. All Staphylococcus spp isolates were sensitive to vancomycin (100%). Conclusion: Pseudomonas aeruginosa was the most predominant organism isolated in otitis media patients. Most of the isolates were sensitive to meropenem.https://www.jcdr.net/articles/PDF/14770/48334_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdfantibioticsear dischargepseudomonas aeruginosastaphylococcus aureus |
| spellingShingle | KIRAN YADAV SANDEEP KAUSHIK KUMKUM RANI ANUJ KUMAR TYAGI Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India Journal of Clinical and Diagnostic Research antibiotics ear discharge pseudomonas aeruginosa staphylococcus aureus |
| title | Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India |
| title_full | Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India |
| title_fullStr | Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India |
| title_full_unstemmed | Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India |
| title_short | Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India |
| title_sort | bacterial profile and antimicrobial susceptibility pattern of chronic suppurative otitis media from a tertiary care hospital in kannauj uttar pradesh india |
| topic | antibiotics ear discharge pseudomonas aeruginosa staphylococcus aureus |
| url | https://www.jcdr.net/articles/PDF/14770/48334_CE[Ra]_F(Sh)_PF1(AG_SL)_PFA(KM)_PB(AG_KM)_PN(KM).pdf |
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