Androgen Receptor-Dependent Mechanisms Mediating Drug Resistance in Prostate Cancer

Androgen Receptor-Dependent Mechanisms Mediating Drug Resistance in Prostate Cancer

Androgen receptor (AR) is a main driver of prostate cancer (PCa) growth and progression as well as the key drug target. Appropriate PCa treatments differ depending on the stage of cancer at diagnosis. Although androgen deprivation therapy (ADT) of PCa is initially effective, eventually tumors develo...

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Bibliographic Details
Main Authors: Marzieh Ehsani, Faith Oluwakemi David, Aria Baniahmad
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
androgen receptor
prostate cancer
AR antagonists
castration resistant PCa
androgen deprivation therapy
Online Access:https://www.mdpi.com/2072-6694/13/7/1534

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