Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms

Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms

Summary: We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell responses, soluble markers of inflammation, and antibody levels and neutralization capacity longitudinally in 70 individuals with PCR-confirmed SARS-CoV-2 infection. Participants represent a spectrum of...

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Bibliographic Details
Main Authors: Michael J. Peluso, Amelia N. Deitchman, Leonel Torres, Nikita S. Iyer, Sadie E. Munter, Christopher C. Nixon, Joanna Donatelli, Cassandra Thanh, Saki Takahashi, Jill Hakim, Keirstinne Turcios, Owen Janson, Rebecca Hoh, Viva Tai, Yanel Hernandez, Emily A. Fehrman, Matthew A. Spinelli, Monica Gandhi, Lan Trinh, Terri Wrin, Christos J. Petropoulos, Francesca T. Aweeka, Isabel Rodriguez-Barraquer, J. Daniel Kelly, Jeffrey N. Martin, Steven G. Deeks, Bryan Greenhouse, Rachel L. Rutishauser, Timothy J. Henrich
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Cell Reports
Subjects:
SARS-CoV-2
COVID-19
T cell
immunity
post-acute sequelae of SARS-CoV-2 infection
PASC
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721009487

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