Long-term in vivo vitamin D3 supplementation modulates bovine IL-1 and chemokine responses
Abstract Vitamin D deficiency at birth, followed by prolonged insufficiency in early life may predispose bovine calves to infection and disease. However, the effects of vitamin D levels on innate immunity are unclear due to the lack of long-term supplementation trials in vivo and reliable approaches...
Main Authors: | Cian Reid, Susana Flores-Villalva, Aude Remot, Emer Kennedy, Cliona O’Farrelly, Kieran G. Meade |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-37427-z |
Similar Items
-
Non-canonical Inflammasome-Mediated IL-1β Production by Primary Endometrial Epithelial and Stromal Fibroblast Cells Is NLRP3 and Caspase-4 Dependent
by: Paul Kelly, et al.
Published: (2019-02-01) -
β-Defensins: Farming the Microbiome for Homeostasis and Health
by: Kieran G. Meade, et al.
Published: (2019-01-01) -
Improved detection of biomarkers in cervico-vaginal mucus (CVM) from postpartum cattle
by: Mounir Adnane, et al.
Published: (2018-09-01) -
The impact of vitamin D3 supplementation on the faecal and oral microbiome of dairy calves indoors or at pasture
by: S. Vigors, et al.
Published: (2023-06-01) -
Low serum vitamin D concentrations in Spring-born dairy calves are associated with elevated peripheral leukocytes
by: Susana Flores-Villalva, et al.
Published: (2021-09-01)