A20 Restricts NOS2 Expression and Intestinal Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

A20 Restricts NOS2 Expression and Intestinal Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Background and Aims: Colon cancer can occur sporadically or in the setting of chronic inflammation, such as in patients with inflammatory bowel disease. We previously showed that A20, a critical negative regulator of tumor necrosis factor signal transduction, could regulate sporadic colon cancer dev...

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Bibliographic Details
Main Authors: David W. Basta, Mandy Vong, Adolat Beshimova, Brooke N. Nakamura, Iulia Rusu, Michael G. Kattah, Ling Shao
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Gastro Hep Advances
Subjects:
Colon
Ulcerative colitis
Inflammation
Nitric oxide
A20
Tnfaip3
Online Access:http://www.sciencedirect.com/science/article/pii/S277257232200156X

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