<i>Datura Metel</i> L. Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis and Inhibits Inflammatory Cytokines Production through TLR7/8–MyD88–NF-κB–NLRP3 Inflammasome Pathway

<i>Datura Metel</i> L. Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis and Inhibits Inflammatory Cytokines Production through TLR7/8–MyD88–NF-κB–NLRP3 Inflammasome Pathway

Background: Psoriasis is a chronic, immune-mediated inflammatory skin disease, and the inflammatory response plays an important role in its development and progression. <i>Datura metel</i> L. is a traditional Chinese medicine that exhibited a significant therapeutic effect on psoriasis i...

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Bibliographic Details
Main Authors: Bing-You Yang, Yan-Gang Cheng, Yan Liu, Yuan Liu, Jin-Yan Tan, Wei Guan, Shuang Guo, Hai-Xue Kuang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
psoriasis
<i>Datura metel</i> L.
imiquimod
inflammatory cytokines
toll-like receptor 7/8
Online Access:https://www.mdpi.com/1420-3049/24/11/2157

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