Gut microbiota turn up the heat after bariatric surgery

Bariatric surgeries like vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) cause well-established shifts in the gut microbiota, but how this contributes to their unique metabolic benefits is poorly understood. Jin et al and Yadav et al now provide two complementary lines of evide...

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Bibliographic Details
Main Author: Mohammed K. Hankir
Format: Article
Language:English
Published: Shared Science Publishers OG 2023-08-01
Series:Cell Stress
Subjects:
Online Access:http://www.cell-stress.com/researcharticles/2023a-hankir-cell-stress/
Description
Summary:Bariatric surgeries like vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) cause well-established shifts in the gut microbiota, but how this contributes to their unique metabolic benefits is poorly understood. Jin et al and Yadav et al now provide two complementary lines of evidence suggesting that gut microbiota-derived metabolites after VSG and RYGB activate thermogenesis in fat through distinct mechanisms, to in turn promote weight loss and/or improvements in glycemic control.
ISSN:2523-0204