Plasmacytoid Dendritic Cells Provide Protection Against Bacterial-Induced Colitis

Plasmacytoid Dendritic Cells Provide Protection Against Bacterial-Induced Colitis

We have examined the influence of depleting plasmacytoid dendritic cells (pDC) in mice on the immune response to the gut pathogen Citrobacter rodentium, an organism that is a model for human attaching effacing pathogens such as enterohaemorraghic E. coli. A significantly higher number of C. rodentiu...

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Bibliographic Details
Main Authors: Tania Rahman, Andrew S. Brown, Elizabeth L. Hartland, Ian R. van Driel, Ka Yee Fung
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
plasmacytoid dendritic cells
Citrobacter rodentium
bacterial gut pathogen
colitis
cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00608/full

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