Analysis of exosome-derived microRNAs as early biomarkers of lipopolysaccharide-induced acute kidney injury in rats

Analysis of exosome-derived microRNAs as early biomarkers of lipopolysaccharide-induced acute kidney injury in rats

Sepsis contributes to the high prevalence of acute kidney injury (AKI), which mainly occurs in hospitalized patients. The delay in AKI detection is a risk factor for death and chronicity; thus, early diagnosis is essential for initiating proper treatment strategies. Although serum creatinine is used...

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Bibliographic Details
Main Authors: Carolina Carvalho Serres Da-Silva, Ana Carolina Anauate, Tatiana Pinotti Guirao, Antônio da Silva Novaes, Edgar Maquigussa, Mirian Aparecida Boim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Physiology
Subjects:
acute kidney injure
sepsis
miRNA
microRNA
exosome (vesicle)
lipopolyssacharide
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.944864/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.944864/full

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