High expression of PDZ-binding kinase is correlated with poor prognosis and immune infiltrates in hepatocellular carcinoma

High expression of PDZ-binding kinase is correlated with poor prognosis and immune infiltrates in hepatocellular carcinoma

Abstract Background PDZ-binding kinase (PBK) encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. There is evidence that overexpression of this gene is associated with tumorigenesis. However, the role of PBK in hepatocellular...

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Bibliographic Details
Main Authors: Wei Mu, Yaoli Xie, Jinhu Li, Runzhi Yan, Jingxian Zhang, Yu’e Liu, Yimin Fan
Format: Article
Language:English
Published: BMC 2022-01-01
Series:World Journal of Surgical Oncology
Subjects:
PDZ-binding kinase (PBK)
Hepatocellular carcinoma (HCC)
Tumor-infiltrating immune cells (TIICs)
Bioinformatics analysis
Signaling pathways
Online Access:https://doi.org/10.1186/s12957-021-02479-w

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