Vasculitic peripheral neuropathy
Primary systemic vasculitis in pre-capillary arteries is associated with peripheral neuropathy. In some types of systematic vasculitis about 60 % of patients have peripheral nervous system (PNS) involvement. In vasculitic peripheral neuropathies (VPN) a necrotizing and inflammatory process leads to...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2014-02-01
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| Series: | Reviews in Clinical Medicine |
| Subjects: | |
| Online Access: | https://rcm.mums.ac.ir/article_2205_8acd27cf72674f1fbd6bab2a3d64e472.pdf |
| _version_ | 1797976065399848960 |
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| author | Mona Amini Reza Boostani Maryam Sahebari |
| author_facet | Mona Amini Reza Boostani Maryam Sahebari |
| author_sort | Mona Amini |
| collection | DOAJ |
| description | Primary systemic vasculitis in pre-capillary arteries is associated with peripheral neuropathy. In some types of systematic vasculitis about 60 % of patients have peripheral nervous system (PNS) involvement. In vasculitic peripheral neuropathies (VPN) a necrotizing and inflammatory process leads to narrowing of vasa nervorum lumen and eventually the appearance of ischemic lesions in peripheral nerves. Some features might be suggestive of VPN, like: axonal nerve degeneration, wallerian-like degeneration, and diameter irregularity of nerve. Peripheral nervous system (PNS) destruction during systemic vasculitides should be considered, due to its frequency and early occurrence in vasculitis progression. The first line treatment of non systematic VPNs is corticosteroid agents, but these drugs might worsen the VPNs or systemic vasculitis. |
| first_indexed | 2024-04-11T04:45:25Z |
| format | Article |
| id | doaj.art-3ca7e0eed8b6491e878bc2ab3354bebf |
| institution | Directory Open Access Journal |
| issn | 2345-6256 2345-6892 |
| language | English |
| last_indexed | 2024-04-11T04:45:25Z |
| publishDate | 2014-02-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Reviews in Clinical Medicine |
| spelling | doaj.art-3ca7e0eed8b6491e878bc2ab3354bebf2022-12-27T13:13:18ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922014-02-0111252810.17463/RCM.2014.01.0072205Vasculitic peripheral neuropathyMona Amini0Reza Boostani1Maryam Sahebari2Department of Neurology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Neurology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Rheumatology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranPrimary systemic vasculitis in pre-capillary arteries is associated with peripheral neuropathy. In some types of systematic vasculitis about 60 % of patients have peripheral nervous system (PNS) involvement. In vasculitic peripheral neuropathies (VPN) a necrotizing and inflammatory process leads to narrowing of vasa nervorum lumen and eventually the appearance of ischemic lesions in peripheral nerves. Some features might be suggestive of VPN, like: axonal nerve degeneration, wallerian-like degeneration, and diameter irregularity of nerve. Peripheral nervous system (PNS) destruction during systemic vasculitides should be considered, due to its frequency and early occurrence in vasculitis progression. The first line treatment of non systematic VPNs is corticosteroid agents, but these drugs might worsen the VPNs or systemic vasculitis.https://rcm.mums.ac.ir/article_2205_8acd27cf72674f1fbd6bab2a3d64e472.pdfmononeuropathyneuropathyvasculitis |
| spellingShingle | Mona Amini Reza Boostani Maryam Sahebari Vasculitic peripheral neuropathy Reviews in Clinical Medicine mononeuropathy neuropathy vasculitis |
| title | Vasculitic peripheral neuropathy |
| title_full | Vasculitic peripheral neuropathy |
| title_fullStr | Vasculitic peripheral neuropathy |
| title_full_unstemmed | Vasculitic peripheral neuropathy |
| title_short | Vasculitic peripheral neuropathy |
| title_sort | vasculitic peripheral neuropathy |
| topic | mononeuropathy neuropathy vasculitis |
| url | https://rcm.mums.ac.ir/article_2205_8acd27cf72674f1fbd6bab2a3d64e472.pdf |
| work_keys_str_mv | AT monaamini vasculiticperipheralneuropathy AT rezaboostani vasculiticperipheralneuropathy AT maryamsahebari vasculiticperipheralneuropathy |