Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes

Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes

Functional studies of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (hCMs) under different gravity conditions contribute to aerospace medical research. To study the effects of altered gravity on hCMs, we exposed them to acute hypergravity and microgravity phases in the presence...

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Bibliographic Details
Main Authors: Aviseka Acharya, Sonja Brungs, Yannick Lichterfeld, Jürgen Hescheler, Ruth Hemmersbach, Helene Boeuf, Agapios Sachinidis
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
microgravity
hypergravity
human induced pluripotent stem cells
cardiomyocytes
adrenoceptor agonist
Isoprenaline
L-type Ca<sup>2+</sup> channels
Bay-K8644
Online Access:https://www.mdpi.com/2073-4409/8/4/352

Internet

https://www.mdpi.com/2073-4409/8/4/352

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