Late-Onset Inadvertent Bleb Formation following Pars Plana M3 Molteno Implant Tube Obstruction

Purpose: To report a case of inadvertent bleb formation presenting 18 months after pars plana M3 Molteno implant tube obstruction in a patient with mixed mechanism glaucoma. Materials and Methods: An 84-year-old Caucasian male with mixed mechanism glaucoma underwent slit-lamp examination, gonioscopy...

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Main Authors: Anmar M. Abdul-Rahman, Anthony Molteno
Format: Article
Language:English
Published: Karger Publishers 2017-01-01
Series:Case Reports in Ophthalmology
Subjects:
Online Access:http://www.karger.com/Article/FullText/456536
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author Anmar M. Abdul-Rahman
Anthony Molteno
author_facet Anmar M. Abdul-Rahman
Anthony Molteno
author_sort Anmar M. Abdul-Rahman
collection DOAJ
description Purpose: To report a case of inadvertent bleb formation presenting 18 months after pars plana M3 Molteno implant tube obstruction in a patient with mixed mechanism glaucoma. Materials and Methods: An 84-year-old Caucasian male with mixed mechanism glaucoma underwent slit-lamp examination, gonioscopy, colour anterior segment photography and anterior segment optical coherence tomography (AS-OCT). Results: An inadvertent bleb developed 18 months after pars plana implant tube re-positioning with a 6/0 Vicryl tie ligature. The bleb was located in the area anterior to the implant plate; it was characterised by a thin, transparent, avascular and multi-cystic wall, with a visible stoma at the posterior edge of the bleb. The bleb was functioning as demonstrated by an intraocular pressure of 6 mm Hg at presentation and a punctate fluorescein uptake pattern of the bleb wall. The bleb over the plate of the Molteno implant was non-functioning, likely secondary to tube obstruction by vitreous in the early postoperative period. AS-OCT showed a tract from the anterior chamber commencing at an entry wound through a corneal tunnel to the posterior stoma at the base of the inadvertent bleb. Conclusions: We hypothesise that the pathophysiologic factors resulting in an inadvertent bleb are a result of a combination of apoptosis, late-onset wound dehiscence and internal gaping of a centrally placed corneal wound. In addition, aqueous hydrodynamic factors may play a role.
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spelling doaj.art-3cab91fdb8ba44e6af27be94b487ffff2022-12-22T03:31:09ZengKarger PublishersCase Reports in Ophthalmology1663-26992017-01-0181738010.1159/000456536456536Late-Onset Inadvertent Bleb Formation following Pars Plana M3 Molteno Implant Tube ObstructionAnmar M. Abdul-RahmanAnthony MoltenoPurpose: To report a case of inadvertent bleb formation presenting 18 months after pars plana M3 Molteno implant tube obstruction in a patient with mixed mechanism glaucoma. Materials and Methods: An 84-year-old Caucasian male with mixed mechanism glaucoma underwent slit-lamp examination, gonioscopy, colour anterior segment photography and anterior segment optical coherence tomography (AS-OCT). Results: An inadvertent bleb developed 18 months after pars plana implant tube re-positioning with a 6/0 Vicryl tie ligature. The bleb was located in the area anterior to the implant plate; it was characterised by a thin, transparent, avascular and multi-cystic wall, with a visible stoma at the posterior edge of the bleb. The bleb was functioning as demonstrated by an intraocular pressure of 6 mm Hg at presentation and a punctate fluorescein uptake pattern of the bleb wall. The bleb over the plate of the Molteno implant was non-functioning, likely secondary to tube obstruction by vitreous in the early postoperative period. AS-OCT showed a tract from the anterior chamber commencing at an entry wound through a corneal tunnel to the posterior stoma at the base of the inadvertent bleb. Conclusions: We hypothesise that the pathophysiologic factors resulting in an inadvertent bleb are a result of a combination of apoptosis, late-onset wound dehiscence and internal gaping of a centrally placed corneal wound. In addition, aqueous hydrodynamic factors may play a role.http://www.karger.com/Article/FullText/456536Inadvertent blebGlaucomaOptical coherence tomographyMolteno implant
spellingShingle Anmar M. Abdul-Rahman
Anthony Molteno
Late-Onset Inadvertent Bleb Formation following Pars Plana M3 Molteno Implant Tube Obstruction
Case Reports in Ophthalmology
Inadvertent bleb
Glaucoma
Optical coherence tomography
Molteno implant
title Late-Onset Inadvertent Bleb Formation following Pars Plana M3 Molteno Implant Tube Obstruction
title_full Late-Onset Inadvertent Bleb Formation following Pars Plana M3 Molteno Implant Tube Obstruction
title_fullStr Late-Onset Inadvertent Bleb Formation following Pars Plana M3 Molteno Implant Tube Obstruction
title_full_unstemmed Late-Onset Inadvertent Bleb Formation following Pars Plana M3 Molteno Implant Tube Obstruction
title_short Late-Onset Inadvertent Bleb Formation following Pars Plana M3 Molteno Implant Tube Obstruction
title_sort late onset inadvertent bleb formation following pars plana m3 molteno implant tube obstruction
topic Inadvertent bleb
Glaucoma
Optical coherence tomography
Molteno implant
url http://www.karger.com/Article/FullText/456536
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