USE OF ZONISAMIDE (ZONEGRAN) IN THE TREATMENT OF EPILEPSY: EMPHASIS ON MONOTHERAPY OF FOCAL SEIZURES (A REVIEW OF FOREIGN LITERATURE)
Despite a considerable advance made in epileptology, resistant epilepsies are about 30 % among all epilepsy types. The paper reviews the current literature dealing with the efficacy and safety of the new antiepileptic drug zonisamide (Zonegran) in the treatment of epilepsy. It describes the mechanis...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2015-04-01
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| Series: | Русский журнал детской неврологии |
| Subjects: | |
| Online Access: | https://rjdn.abvpress.ru/jour/article/view/21 |
| _version_ | 1797874463256084480 |
|---|---|
| author | O. A. Pylaeva K. Yu. Mukhin |
| author_facet | O. A. Pylaeva K. Yu. Mukhin |
| author_sort | O. A. Pylaeva |
| collection | DOAJ |
| description | Despite a considerable advance made in epileptology, resistant epilepsies are about 30 % among all epilepsy types. The paper reviews the current literature dealing with the efficacy and safety of the new antiepileptic drug zonisamide (Zonegran) in the treatment of epilepsy. It describes the mechanism of action, pharmacokinetics, efficacy, and tolerability of zonisamide in resistant epilepsy. The authors focus their attention on recent trials of zonisamide used in monotherapy. |
| first_indexed | 2024-04-10T01:32:25Z |
| format | Article |
| id | doaj.art-3cb1e2872c8940caa9c091b11210eed8 |
| institution | Directory Open Access Journal |
| issn | 2073-8803 2412-9178 |
| language | Russian |
| last_indexed | 2024-04-10T01:32:25Z |
| publishDate | 2015-04-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Русский журнал детской неврологии |
| spelling | doaj.art-3cb1e2872c8940caa9c091b11210eed82023-03-13T09:30:10ZrusABV-pressРусский журнал детской неврологии2073-88032412-91782015-04-0192424910.17650/2073-8803-2014-9-2-42-4915USE OF ZONISAMIDE (ZONEGRAN) IN THE TREATMENT OF EPILEPSY: EMPHASIS ON MONOTHERAPY OF FOCAL SEIZURES (A REVIEW OF FOREIGN LITERATURE)O. A. Pylaeva0K. Yu. Mukhin1ООО «Институт детской неврологии и эпилепсии им. Святителя Луки», МоскваООО «Институт детской неврологии и эпилепсии им. Святителя Луки», МоскваDespite a considerable advance made in epileptology, resistant epilepsies are about 30 % among all epilepsy types. The paper reviews the current literature dealing with the efficacy and safety of the new antiepileptic drug zonisamide (Zonegran) in the treatment of epilepsy. It describes the mechanism of action, pharmacokinetics, efficacy, and tolerability of zonisamide in resistant epilepsy. The authors focus their attention on recent trials of zonisamide used in monotherapy.https://rjdn.abvpress.ru/jour/article/view/21эпилепсиязонисамидфокальные приступымонотерапияэффективностьпереносимость |
| spellingShingle | O. A. Pylaeva K. Yu. Mukhin USE OF ZONISAMIDE (ZONEGRAN) IN THE TREATMENT OF EPILEPSY: EMPHASIS ON MONOTHERAPY OF FOCAL SEIZURES (A REVIEW OF FOREIGN LITERATURE) Русский журнал детской неврологии эпилепсия зонисамид фокальные приступы монотерапия эффективность переносимость |
| title | USE OF ZONISAMIDE (ZONEGRAN) IN THE TREATMENT OF EPILEPSY: EMPHASIS ON MONOTHERAPY OF FOCAL SEIZURES (A REVIEW OF FOREIGN LITERATURE) |
| title_full | USE OF ZONISAMIDE (ZONEGRAN) IN THE TREATMENT OF EPILEPSY: EMPHASIS ON MONOTHERAPY OF FOCAL SEIZURES (A REVIEW OF FOREIGN LITERATURE) |
| title_fullStr | USE OF ZONISAMIDE (ZONEGRAN) IN THE TREATMENT OF EPILEPSY: EMPHASIS ON MONOTHERAPY OF FOCAL SEIZURES (A REVIEW OF FOREIGN LITERATURE) |
| title_full_unstemmed | USE OF ZONISAMIDE (ZONEGRAN) IN THE TREATMENT OF EPILEPSY: EMPHASIS ON MONOTHERAPY OF FOCAL SEIZURES (A REVIEW OF FOREIGN LITERATURE) |
| title_short | USE OF ZONISAMIDE (ZONEGRAN) IN THE TREATMENT OF EPILEPSY: EMPHASIS ON MONOTHERAPY OF FOCAL SEIZURES (A REVIEW OF FOREIGN LITERATURE) |
| title_sort | use of zonisamide zonegran in the treatment of epilepsy emphasis on monotherapy of focal seizures a review of foreign literature |
| topic | эпилепсия зонисамид фокальные приступы монотерапия эффективность переносимость |
| url | https://rjdn.abvpress.ru/jour/article/view/21 |
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