Changes in NMDA Receptor Function in Rapid Ischemic Tolerance: A Potential Role for Tri-Heteromeric NMDA Receptors

Changes in NMDA Receptor Function in Rapid Ischemic Tolerance: A Potential Role for Tri-Heteromeric NMDA Receptors

In this study, we characterize biophysical changes in NMDA receptor function in response to brief non-injurious ischemic stress (ischemic preconditioning). Electrophysiological studies show NMDA receptor function is reduced following preconditioning in cultured rat cortical neurons. This functional...

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Bibliographic Details
Main Authors: Mian Xie, Tiandong Leng, Samaneh Maysami, Andrea Pearson, Roger Simon, Zhi-Gang Xiong, Robert Meller
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomolecules
Subjects:
NMDA receptor
ischemic preconditioning
ischemic tolerance
oxygen and glucose deprivation
Online Access:https://www.mdpi.com/2218-273X/12/9/1214

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