Total knee arthroplasty and femoral osteotomy with a patient-specific cutting guide to treat haemophilic arthritis with severe extra-articular deformity: A case report and review of literatures

BackgroundTotal knee arthroplasty (TKA) is recommended for haemophilic patients with end-stage arthritis. TKA combined with a one-stage extraarticular osteotomy is uncommon in the treatment of haemophilic arthritis (HA) with severe extra-articular deformities (EADs) and a history of inhibitors under...

Full description

Bibliographic Details
Main Authors: Shuai-Jie Lv, Zheng-Ming Wang, Rui Wang, Heng-Kai Jin, Pei-Jian Tong, Xun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2022.1067306/full
_version_ 1797960057586974720
author Shuai-Jie Lv
Zheng-Ming Wang
Rui Wang
Heng-Kai Jin
Pei-Jian Tong
Xun Liu
author_facet Shuai-Jie Lv
Zheng-Ming Wang
Rui Wang
Heng-Kai Jin
Pei-Jian Tong
Xun Liu
author_sort Shuai-Jie Lv
collection DOAJ
description BackgroundTotal knee arthroplasty (TKA) is recommended for haemophilic patients with end-stage arthritis. TKA combined with a one-stage extraarticular osteotomy is uncommon in the treatment of haemophilic arthritis (HA) with severe extra-articular deformities (EADs) and a history of inhibitors under the guidance of a patient-specific cutting guide (PSI).Case presentationWe reported a 20-year-old male patient with severe haemophilia, limited knee functionality, a 30° sagittal deformity on the femoral side and a history of inhibitors. We adopted the Van Creveld protocol to decrease the inhibitors. TKA and extra-articular osteotomy (EAO) were performed simultaneously and sequentially under the guidance of PSI. An appropriate central alignment of the lower limb was restored by using cement prostheses with antibiotics and femur shaft locking compression plates. The last follow-up showed that the knee function was good, the VAS score was 0, the WOMAC score was 18 and the ROM was 0°–95°.ConclisionRegular haematology management can reduce the perioperative bleeding risk in haemophilic patients treated with inhibitors. PSI plays an important role in guiding the TKA and EAO of end-stage HA patients with severe EAD.
first_indexed 2024-04-11T00:40:03Z
format Article
id doaj.art-3cb53141cd694e44a827af2b3e27e1b7
institution Directory Open Access Journal
issn 2296-875X
language English
last_indexed 2024-04-11T00:40:03Z
publishDate 2023-01-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Surgery
spelling doaj.art-3cb53141cd694e44a827af2b3e27e1b72023-01-06T07:15:04ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-01-01910.3389/fsurg.2022.10673061067306Total knee arthroplasty and femoral osteotomy with a patient-specific cutting guide to treat haemophilic arthritis with severe extra-articular deformity: A case report and review of literaturesShuai-Jie Lv0Zheng-Ming Wang1Rui Wang2Heng-Kai Jin3Pei-Jian Tong4Xun Liu5Orthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ChinaShi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaThe First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, ChinaThe First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, ChinaOrthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ChinaOrthopedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ChinaBackgroundTotal knee arthroplasty (TKA) is recommended for haemophilic patients with end-stage arthritis. TKA combined with a one-stage extraarticular osteotomy is uncommon in the treatment of haemophilic arthritis (HA) with severe extra-articular deformities (EADs) and a history of inhibitors under the guidance of a patient-specific cutting guide (PSI).Case presentationWe reported a 20-year-old male patient with severe haemophilia, limited knee functionality, a 30° sagittal deformity on the femoral side and a history of inhibitors. We adopted the Van Creveld protocol to decrease the inhibitors. TKA and extra-articular osteotomy (EAO) were performed simultaneously and sequentially under the guidance of PSI. An appropriate central alignment of the lower limb was restored by using cement prostheses with antibiotics and femur shaft locking compression plates. The last follow-up showed that the knee function was good, the VAS score was 0, the WOMAC score was 18 and the ROM was 0°–95°.ConclisionRegular haematology management can reduce the perioperative bleeding risk in haemophilic patients treated with inhibitors. PSI plays an important role in guiding the TKA and EAO of end-stage HA patients with severe EAD.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1067306/fullhaemophilic arthritisextra-articular deformityPSItotal knee arthroplastycase report
spellingShingle Shuai-Jie Lv
Zheng-Ming Wang
Rui Wang
Heng-Kai Jin
Pei-Jian Tong
Xun Liu
Total knee arthroplasty and femoral osteotomy with a patient-specific cutting guide to treat haemophilic arthritis with severe extra-articular deformity: A case report and review of literatures
Frontiers in Surgery
haemophilic arthritis
extra-articular deformity
PSI
total knee arthroplasty
case report
title Total knee arthroplasty and femoral osteotomy with a patient-specific cutting guide to treat haemophilic arthritis with severe extra-articular deformity: A case report and review of literatures
title_full Total knee arthroplasty and femoral osteotomy with a patient-specific cutting guide to treat haemophilic arthritis with severe extra-articular deformity: A case report and review of literatures
title_fullStr Total knee arthroplasty and femoral osteotomy with a patient-specific cutting guide to treat haemophilic arthritis with severe extra-articular deformity: A case report and review of literatures
title_full_unstemmed Total knee arthroplasty and femoral osteotomy with a patient-specific cutting guide to treat haemophilic arthritis with severe extra-articular deformity: A case report and review of literatures
title_short Total knee arthroplasty and femoral osteotomy with a patient-specific cutting guide to treat haemophilic arthritis with severe extra-articular deformity: A case report and review of literatures
title_sort total knee arthroplasty and femoral osteotomy with a patient specific cutting guide to treat haemophilic arthritis with severe extra articular deformity a case report and review of literatures
topic haemophilic arthritis
extra-articular deformity
PSI
total knee arthroplasty
case report
url https://www.frontiersin.org/articles/10.3389/fsurg.2022.1067306/full
work_keys_str_mv AT shuaijielv totalkneearthroplastyandfemoralosteotomywithapatientspecificcuttingguidetotreathaemophilicarthritiswithsevereextraarticulardeformityacasereportandreviewofliteratures
AT zhengmingwang totalkneearthroplastyandfemoralosteotomywithapatientspecificcuttingguidetotreathaemophilicarthritiswithsevereextraarticulardeformityacasereportandreviewofliteratures
AT ruiwang totalkneearthroplastyandfemoralosteotomywithapatientspecificcuttingguidetotreathaemophilicarthritiswithsevereextraarticulardeformityacasereportandreviewofliteratures
AT hengkaijin totalkneearthroplastyandfemoralosteotomywithapatientspecificcuttingguidetotreathaemophilicarthritiswithsevereextraarticulardeformityacasereportandreviewofliteratures
AT peijiantong totalkneearthroplastyandfemoralosteotomywithapatientspecificcuttingguidetotreathaemophilicarthritiswithsevereextraarticulardeformityacasereportandreviewofliteratures
AT xunliu totalkneearthroplastyandfemoralosteotomywithapatientspecificcuttingguidetotreathaemophilicarthritiswithsevereextraarticulardeformityacasereportandreviewofliteratures