ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
The purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and show...
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Format: | Article |
Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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Series: | Разработка и регистрация лекарственных средств |
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Online Access: | https://www.pharmjournal.ru/jour/article/view/237 |
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author | E. V. Ponomarenko |
author_facet | E. V. Ponomarenko |
author_sort | E. V. Ponomarenko |
collection | DOAJ |
description | The purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and shows that the studied compound exhibits antiadrenergic effect and potentiates the effect of exogenous insulin. |
first_indexed | 2024-04-10T01:41:12Z |
format | Article |
id | doaj.art-3cb60c8344e34fde8eb0e62a9ee6cdf2 |
institution | Directory Open Access Journal |
issn | 2305-2066 2658-5049 |
language | Russian |
last_indexed | 2024-04-10T01:41:12Z |
publishDate | 2019-01-01 |
publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
record_format | Article |
series | Разработка и регистрация лекарственных средств |
spelling | doaj.art-3cb60c8344e34fde8eb0e62a9ee6cdf22023-03-13T09:13:57ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101172175237ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATEE. V. Ponomarenko0ГБОУ ВПО «Пермская государственная фармацевтическая академия» Министерства здравоохранения Российской ФедерацииThe purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and shows that the studied compound exhibits antiadrenergic effect and potentiates the effect of exogenous insulin.https://www.pharmjournal.ru/jour/article/view/237противодиабетическая активностьантиадренэргическое действиегипогликемический эффект |
spellingShingle | E. V. Ponomarenko ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE Разработка и регистрация лекарственных средств противодиабетическая активность антиадренэргическое действие гипогликемический эффект |
title | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
title_full | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
title_fullStr | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
title_full_unstemmed | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
title_short | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
title_sort | antidiabetic activity of guanidinium salt 2 aminophenylacetate |
topic | противодиабетическая активность антиадренэргическое действие гипогликемический эффект |
url | https://www.pharmjournal.ru/jour/article/view/237 |
work_keys_str_mv | AT evponomarenko antidiabeticactivityofguanidiniumsalt2aminophenylacetate |