ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE

The purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and show...

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Main Author: E. V. Ponomarenko
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/237
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author E. V. Ponomarenko
author_facet E. V. Ponomarenko
author_sort E. V. Ponomarenko
collection DOAJ
description The purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and shows that the studied compound exhibits antiadrenergic effect and potentiates the effect of exogenous insulin.
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last_indexed 2024-04-10T01:41:12Z
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publisher LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
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spelling doaj.art-3cb60c8344e34fde8eb0e62a9ee6cdf22023-03-13T09:13:57ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101172175237ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATEE. V. Ponomarenko0ГБОУ ВПО «Пермская государственная фармацевтическая академия» Министерства здравоохранения Российской ФедерацииThe purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and shows that the studied compound exhibits antiadrenergic effect and potentiates the effect of exogenous insulin.https://www.pharmjournal.ru/jour/article/view/237противодиабетическая активностьантиадренэргическое действиегипогликемический эффект
spellingShingle E. V. Ponomarenko
ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
Разработка и регистрация лекарственных средств
противодиабетическая активность
антиадренэргическое действие
гипогликемический эффект
title ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
title_full ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
title_fullStr ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
title_full_unstemmed ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
title_short ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
title_sort antidiabetic activity of guanidinium salt 2 aminophenylacetate
topic противодиабетическая активность
антиадренэргическое действие
гипогликемический эффект
url https://www.pharmjournal.ru/jour/article/view/237
work_keys_str_mv AT evponomarenko antidiabeticactivityofguanidiniumsalt2aminophenylacetate