Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome
The gut microbiomes of non-human primates have received a great deal of attention due to their close relationship to humans. In recent years, these studies have mainly focused on the gut microbiome of wild primates, which will be helpful to understanding the evolution of primates and their gut micro...
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Elsevier
2022-01-01
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| Series: | Computational and Structural Biotechnology Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037022000186 |
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| author | Wancai Xia Guoqi Liu Dali Wang Hua Chen Lifeng Zhu Dayong Li |
| author_facet | Wancai Xia Guoqi Liu Dali Wang Hua Chen Lifeng Zhu Dayong Li |
| author_sort | Wancai Xia |
| collection | DOAJ |
| description | The gut microbiomes of non-human primates have received a great deal of attention due to their close relationship to humans. In recent years, these studies have mainly focused on the gut microbiome of wild primates, which will be helpful to understanding the evolution of primates and their gut microbiomes (e.g., gut microbiome plasticity and diet flexibility). However, there is still a lack of basic information on the gut microbiomes from wild populations. Here, we investigated the gut microbial composition (16S rRNA gene) and function (metagenome and metagenome-assembled genomes (MAGs)) of Yunnan snub-nosed monkey populations in Weixi County, Yunnan Province, China, that had diets either completely based on wild-foraging or were regularly supplemented with human provisioned food. We found a significant difference in the gut microbiome between these two populations: the gut microbiome of the wild-foraging (no food provision) population was enriched genes involved in the detoxification of bamboo cyanide (high proportion of bamboo shoot intake) and chitin (from insect diet) digestion, while the gut microbiome of the food provisioned (e.g., fruits) wild populations were enriched genes involved in carbohydrate metabolism. Moreover, the gut microbiome of the wild-foraging population shared a putatively functional convergence with the gut microbiome of wild bamboo-eating pandas: such as microbes and genes involved in the cyanide detoxification. Therefore, the gut microbiome of the Yunnan snub-nosed monkey displayed the potential plasticity in response to diet flexibility. Long-term food-provisioning of the wild population has led to dramatic changes in gut microbial composition, function, and even antibiotic resistance. The antibiotic resistance profile for the wild Yunnan snub-nosed monkey population could be considered the baseline and an important piece of information for conservation. |
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| institution | Directory Open Access Journal |
| issn | 2001-0370 |
| language | English |
| last_indexed | 2024-04-11T05:20:16Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
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| series | Computational and Structural Biotechnology Journal |
| spelling | doaj.art-3cb6e04869014311bdbcf7be9ab76b2b2022-12-24T04:51:15ZengElsevierComputational and Structural Biotechnology Journal2001-03702022-01-0120685699Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiomeWancai Xia0Guoqi Liu1Dali Wang2Hua Chen3Lifeng Zhu4Dayong Li5Key Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education), China West Normal University, Nanchong, Sichuan, China; Institute of Rare Animals and Plants, China West Normal University, Nanchong, Sichuan, ChinaMingke Biotechnology, Hangzhou, ChinaKey Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education), China West Normal University, Nanchong, Sichuan, China; Institute of Rare Animals and Plants, China West Normal University, Nanchong, Sichuan, ChinaMingke Biotechnology, Hangzhou, ChinaCollege of Life Sciences, Nanjing Normal University, Nanjing, China; Corresponding authors at: College of Life Science, Nanjing Normal University, Nanjing, China (L. Zhu); Key Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education), Nanchong, China West Normal University, China (D. Li).Key Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education), China West Normal University, Nanchong, Sichuan, China; Institute of Rare Animals and Plants, China West Normal University, Nanchong, Sichuan, China; Corresponding authors at: College of Life Science, Nanjing Normal University, Nanjing, China (L. Zhu); Key Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education), Nanchong, China West Normal University, China (D. Li).The gut microbiomes of non-human primates have received a great deal of attention due to their close relationship to humans. In recent years, these studies have mainly focused on the gut microbiome of wild primates, which will be helpful to understanding the evolution of primates and their gut microbiomes (e.g., gut microbiome plasticity and diet flexibility). However, there is still a lack of basic information on the gut microbiomes from wild populations. Here, we investigated the gut microbial composition (16S rRNA gene) and function (metagenome and metagenome-assembled genomes (MAGs)) of Yunnan snub-nosed monkey populations in Weixi County, Yunnan Province, China, that had diets either completely based on wild-foraging or were regularly supplemented with human provisioned food. We found a significant difference in the gut microbiome between these two populations: the gut microbiome of the wild-foraging (no food provision) population was enriched genes involved in the detoxification of bamboo cyanide (high proportion of bamboo shoot intake) and chitin (from insect diet) digestion, while the gut microbiome of the food provisioned (e.g., fruits) wild populations were enriched genes involved in carbohydrate metabolism. Moreover, the gut microbiome of the wild-foraging population shared a putatively functional convergence with the gut microbiome of wild bamboo-eating pandas: such as microbes and genes involved in the cyanide detoxification. Therefore, the gut microbiome of the Yunnan snub-nosed monkey displayed the potential plasticity in response to diet flexibility. Long-term food-provisioning of the wild population has led to dramatic changes in gut microbial composition, function, and even antibiotic resistance. The antibiotic resistance profile for the wild Yunnan snub-nosed monkey population could be considered the baseline and an important piece of information for conservation.http://www.sciencedirect.com/science/article/pii/S2001037022000186Yunnan snob-nosed monkeyDietary flexibilityMetagenomeMetagenome-assembled genomesGut microbiome plasticityFunctional convergence |
| spellingShingle | Wancai Xia Guoqi Liu Dali Wang Hua Chen Lifeng Zhu Dayong Li Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome Computational and Structural Biotechnology Journal Yunnan snob-nosed monkey Dietary flexibility Metagenome Metagenome-assembled genomes Gut microbiome plasticity Functional convergence |
| title | Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome |
| title_full | Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome |
| title_fullStr | Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome |
| title_full_unstemmed | Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome |
| title_short | Functional convergence of Yunnan snub-nosed monkey and bamboo-eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome |
| title_sort | functional convergence of yunnan snub nosed monkey and bamboo eating panda gut microbiomes revealing the driving by dietary flexibility on mammal gut microbiome |
| topic | Yunnan snob-nosed monkey Dietary flexibility Metagenome Metagenome-assembled genomes Gut microbiome plasticity Functional convergence |
| url | http://www.sciencedirect.com/science/article/pii/S2001037022000186 |
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