Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis.

Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis.

In mitosis, the spindle assembly checkpoint (SAC) prevents anaphase onset until all chromosomes have been attached to the spindle microtubules and aligned correctly at the equatorial metaphase plate. The major checkpoint proteins in mitosis consist of mitotic arrest-deficient (Mad)1-3, budding uninh...

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Bibliographic Details
Main Authors: Mo Li, Sen Li, Ju Yuan, Zhen-Bo Wang, Shao-Chen Sun, Heide Schatten, Qing-Yuan Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2765619?pdf=render

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