Glucogallin Attenuates the LPS-Induced Signaling in Macrophages and Protects Mice against Sepsis

Glucogallin Attenuates the LPS-Induced Signaling in Macrophages and Protects Mice against Sepsis

The anti-oxidant and anti-inflammatory effect of beta-glucogallin (BGG), a plant-derived natural product, was evaluated in both in vitro and in vivo studies. For the in vitro study, the ability of BGG pre-treatment to quench LPS-induced effects compared to LPS alone in macrophages was investigated....

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Bibliographic Details
Main Authors: Rajveer Singh, Shivani Chandel, Arijit Ghosh, Tushar Matta, Anupam Gautam, Arka Bhattacharya, Srivalliputturu Sarath Babu, Soumi Sukla, Debasish Nag, Velayutham Ravichandiran, Syamal Roy, Dipanjan Ghosh
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
beta-glucogallin
lipopolysaccharide
macrophages
gene expression profiling
anti-inflammatory
sepsis
Online Access:https://www.mdpi.com/1422-0067/23/19/11254

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https://www.mdpi.com/1422-0067/23/19/11254

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