On-chip constructive cell-network study (II): on-chip quasi-<it>in vivo </it>cardiac toxicity assay for ventricular tachycardia/fibrillation measurement using ring-shaped closed circuit microelectrode with lined-up cardiomyocyte cell network

<p>Abstract</p> <p>Backgrounds</p> <p>Conventional <it>in vitro </it>approach using human ether-a-go-go related gene (hERG) assay has been considered worldwide as the first screening assay for cardiac repolarization safety. However, it does not always oredic...

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Bibliographic Details
Main Authors: Yasuda Kenji, Hattori Akihiro, Kaneko Tomoyuki, Nomura Fumimasa
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Journal of Nanobiotechnology
Online Access:http://www.jnanobiotechnology.com/content/9/1/39