Royan Institute First Attempts: Autotransplantation of Vitrified Human Ovarian Tissue in Cancer Patients
Today, timely diagnosis and therapeutic progress open a road of hope for survival in cancerous patients. Increasedknowledge about the various cytotoxic treatment's impacts on ovarian function and fertility has resulted in a surgein the number of patients seeking to preserve their fertility befo...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Royan Institute (ACECR), Tehran
2023-11-01
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| Series: | Cell Journal |
| Subjects: | |
| Online Access: | https://www.celljournal.org/article_706589_2d32575e8a1dd1f059b53f9a73482fa3.pdf |
| _version_ | 1797398760054063104 |
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| author | Naeimeh Sadat Abtahi Bita Ebrahimi Firouzeh Ghaffari Rohollah Fathi Mojtaba Rezazadeh Valojerdi Abolfazl Mehdizadeh Kashi Sepideh Khodaverdi Azar Yahyaei Maziar Faridi |
| author_facet | Naeimeh Sadat Abtahi Bita Ebrahimi Firouzeh Ghaffari Rohollah Fathi Mojtaba Rezazadeh Valojerdi Abolfazl Mehdizadeh Kashi Sepideh Khodaverdi Azar Yahyaei Maziar Faridi |
| author_sort | Naeimeh Sadat Abtahi |
| collection | DOAJ |
| description | Today, timely diagnosis and therapeutic progress open a road of hope for survival in cancerous patients. Increasedknowledge about the various cytotoxic treatment's impacts on ovarian function and fertility has resulted in a surgein the number of patients seeking to preserve their fertility before starting the anti-cancer treatment process. In thisregard, embryo cryopreservation can be recommended for fertility preservation when the woman is married and hasadequate time for ovarian stimulation. If patients are prepubertal girls or not married women, oocytes or ovarian tissuecan be frozen instead to be used in the future. In this regard, the first attempts for ovarian tissue transplantations wereconducted in 2016 and in 2019 for two cancerous patients whose ovarian tissue was cryopreserved in the RoyanHuman Ovarian Tissue Bank (Tehran, Iran). Unfortunately, the transplantations did not result in a live birth. |
| first_indexed | 2024-03-09T01:30:09Z |
| format | Article |
| id | doaj.art-3cd73f582b6742f78a6c85c11d8a9088 |
| institution | Directory Open Access Journal |
| issn | 2228-5806 2228-5814 |
| language | English |
| last_indexed | 2024-03-09T01:30:09Z |
| publishDate | 2023-11-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | Cell Journal |
| spelling | doaj.art-3cd73f582b6742f78a6c85c11d8a90882023-12-10T05:27:04ZengRoyan Institute (ACECR), TehranCell Journal2228-58062228-58142023-11-01251180981210.22074/cellj.2023.2000360.1289706589Royan Institute First Attempts: Autotransplantation of Vitrified Human Ovarian Tissue in Cancer PatientsNaeimeh Sadat Abtahi0Bita Ebrahimi1Firouzeh Ghaffari2Rohollah Fathi3Mojtaba Rezazadeh Valojerdi4Abolfazl Mehdizadeh Kashi5Sepideh Khodaverdi6Azar Yahyaei7Maziar Faridi8Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranEndometriosis Research Center, Iran University of Medical Sciences, Tehran, IranEndometriosis Research Center, Iran University of Medical Sciences, Tehran, IranDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Surgery, Iranmehr Hospital, Tehran, IranToday, timely diagnosis and therapeutic progress open a road of hope for survival in cancerous patients. Increasedknowledge about the various cytotoxic treatment's impacts on ovarian function and fertility has resulted in a surgein the number of patients seeking to preserve their fertility before starting the anti-cancer treatment process. In thisregard, embryo cryopreservation can be recommended for fertility preservation when the woman is married and hasadequate time for ovarian stimulation. If patients are prepubertal girls or not married women, oocytes or ovarian tissuecan be frozen instead to be used in the future. In this regard, the first attempts for ovarian tissue transplantations wereconducted in 2016 and in 2019 for two cancerous patients whose ovarian tissue was cryopreserved in the RoyanHuman Ovarian Tissue Bank (Tehran, Iran). Unfortunately, the transplantations did not result in a live birth.https://www.celljournal.org/article_706589_2d32575e8a1dd1f059b53f9a73482fa3.pdffertility preservationhumanoncofertilityovarian tissuetransplantation |
| spellingShingle | Naeimeh Sadat Abtahi Bita Ebrahimi Firouzeh Ghaffari Rohollah Fathi Mojtaba Rezazadeh Valojerdi Abolfazl Mehdizadeh Kashi Sepideh Khodaverdi Azar Yahyaei Maziar Faridi Royan Institute First Attempts: Autotransplantation of Vitrified Human Ovarian Tissue in Cancer Patients Cell Journal fertility preservation human oncofertility ovarian tissue transplantation |
| title | Royan Institute First Attempts: Autotransplantation of Vitrified Human Ovarian Tissue in Cancer Patients |
| title_full | Royan Institute First Attempts: Autotransplantation of Vitrified Human Ovarian Tissue in Cancer Patients |
| title_fullStr | Royan Institute First Attempts: Autotransplantation of Vitrified Human Ovarian Tissue in Cancer Patients |
| title_full_unstemmed | Royan Institute First Attempts: Autotransplantation of Vitrified Human Ovarian Tissue in Cancer Patients |
| title_short | Royan Institute First Attempts: Autotransplantation of Vitrified Human Ovarian Tissue in Cancer Patients |
| title_sort | royan institute first attempts autotransplantation of vitrified human ovarian tissue in cancer patients |
| topic | fertility preservation human oncofertility ovarian tissue transplantation |
| url | https://www.celljournal.org/article_706589_2d32575e8a1dd1f059b53f9a73482fa3.pdf |
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