The Anti-Inflammatory Activity of Nigella sativa Balm Sticks
Nigella sativa oil has been known to have potent anti-inflammatory activity. This research aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical application. The activity was checked using two methods: carrageenan-induced paw oedema and granuloma p...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-01-01
|
| Series: | Scientia Pharmaceutica |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2218-0532/87/1/3 |
| _version_ | 1798034232705024000 |
|---|---|
| author | Lusi Putri Dwita Kori Yati Sri Nevi Gantini |
| author_facet | Lusi Putri Dwita Kori Yati Sri Nevi Gantini |
| author_sort | Lusi Putri Dwita |
| collection | DOAJ |
| description | Nigella sativa oil has been known to have potent anti-inflammatory activity. This research aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical application. The activity was checked using two methods: carrageenan-induced paw oedema and granuloma pouch on rats. The results showed that balm sticks which contained 10% Nigella sativa could overcome both acute and sub-acute inflammation showing by high oedema inhibition (60.64%), low leucocytes count (43.55% lower than control) as well as a notable TNF-α concentration (50% lower than control) on the inflamed area. In conclusion, topical application of a Nigella sativa balm stick was effective for both acute and sub-acute forms of inflammation. |
| first_indexed | 2024-04-11T20:41:30Z |
| format | Article |
| id | doaj.art-3cd75801a09f4e0fb2ac18314337283e |
| institution | Directory Open Access Journal |
| issn | 2218-0532 |
| language | English |
| last_indexed | 2024-04-11T20:41:30Z |
| publishDate | 2019-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Scientia Pharmaceutica |
| spelling | doaj.art-3cd75801a09f4e0fb2ac18314337283e2022-12-22T04:04:12ZengMDPI AGScientia Pharmaceutica2218-05322019-01-01871310.3390/scipharm87010003scipharm87010003The Anti-Inflammatory Activity of Nigella sativa Balm SticksLusi Putri Dwita0Kori Yati1Sri Nevi Gantini2Department of Pharmacy and Science, Universitas Muhammadiyah Prof. Dr HAMKA (UHAMKA), Jakarta 13460, IndonesiaDepartment of Pharmacy and Science, Universitas Muhammadiyah Prof. Dr HAMKA (UHAMKA), Jakarta 13460, IndonesiaDepartment of Pharmacy and Science, Universitas Muhammadiyah Prof. Dr HAMKA (UHAMKA), Jakarta 13460, IndonesiaNigella sativa oil has been known to have potent anti-inflammatory activity. This research aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical application. The activity was checked using two methods: carrageenan-induced paw oedema and granuloma pouch on rats. The results showed that balm sticks which contained 10% Nigella sativa could overcome both acute and sub-acute inflammation showing by high oedema inhibition (60.64%), low leucocytes count (43.55% lower than control) as well as a notable TNF-α concentration (50% lower than control) on the inflamed area. In conclusion, topical application of a Nigella sativa balm stick was effective for both acute and sub-acute forms of inflammation.http://www.mdpi.com/2218-0532/87/1/3Nigella sativaanti-inflammatorybalmtopical |
| spellingShingle | Lusi Putri Dwita Kori Yati Sri Nevi Gantini The Anti-Inflammatory Activity of Nigella sativa Balm Sticks Scientia Pharmaceutica Nigella sativa anti-inflammatory balm topical |
| title | The Anti-Inflammatory Activity of Nigella sativa Balm Sticks |
| title_full | The Anti-Inflammatory Activity of Nigella sativa Balm Sticks |
| title_fullStr | The Anti-Inflammatory Activity of Nigella sativa Balm Sticks |
| title_full_unstemmed | The Anti-Inflammatory Activity of Nigella sativa Balm Sticks |
| title_short | The Anti-Inflammatory Activity of Nigella sativa Balm Sticks |
| title_sort | anti inflammatory activity of nigella sativa balm sticks |
| topic | Nigella sativa anti-inflammatory balm topical |
| url | http://www.mdpi.com/2218-0532/87/1/3 |
| work_keys_str_mv | AT lusiputridwita theantiinflammatoryactivityofnigellasativabalmsticks AT koriyati theantiinflammatoryactivityofnigellasativabalmsticks AT srinevigantini theantiinflammatoryactivityofnigellasativabalmsticks AT lusiputridwita antiinflammatoryactivityofnigellasativabalmsticks AT koriyati antiinflammatoryactivityofnigellasativabalmsticks AT srinevigantini antiinflammatoryactivityofnigellasativabalmsticks |