Hydroxyapatite/TiO<sub>2</sub> Nanomaterial with Defined Microstructural and Good Antimicrobial Properties
Due to the growing number of people infected with the new coronavirus globally, which weakens immunity, there has been an increase in bacterial infections. Hence, knowledge about simple and low-cost synthesis methods of materials with good structural and antimicrobial properties is of great importan...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/11/5/592 |
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| author | Miljana Mirković Suzana Filipović Ana Kalijadis Pavle Mašković Jelena Mašković Branislav Vlahović Vladimir Pavlović |
| author_facet | Miljana Mirković Suzana Filipović Ana Kalijadis Pavle Mašković Jelena Mašković Branislav Vlahović Vladimir Pavlović |
| author_sort | Miljana Mirković |
| collection | DOAJ |
| description | Due to the growing number of people infected with the new coronavirus globally, which weakens immunity, there has been an increase in bacterial infections. Hence, knowledge about simple and low-cost synthesis methods of materials with good structural and antimicrobial properties is of great importance. A material obtained through the combination of a nanoscale hydroxyapatite material (with good biocompatibility) and titanium dioxide (with good degradation properties of organic molecules) can absorb and decompose bacteria. In this investigation, three different synthesis routes used to prepare hydroxyapatite/titanium dioxide nanomaterials are examined. The morphology and semiquantitative chemical composition are characterized by scanning electron microscopy with energy dispersive X-ray analysis (SEM-EDX). The obtained materials’ phase and structural characterization are determined using the X-ray powder diffraction method (XRD). The crystallite sizes of the obtained materials are in the range of 8 nm to 15 nm. Based on XRD peak positions, the hexagonal hydroxyapatite phases are formed in all samples along with TiO<sub>2</sub> anatase and rutile phases. According to SEM and TEM analyses, the morphology of the prepared samples differs depending on the synthesis route. The EDX analysis confirmed the presence of Ti, Ca, P, and O in the obtained materials. The IR spectroscopy verified the vibration bands characteristic for HAp and titanium. The investigated materials show excellent antimicrobial and photocatalytic properties. |
| first_indexed | 2024-03-10T03:27:09Z |
| format | Article |
| id | doaj.art-3cdf224b0b734e0faf658af60a734427 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T03:27:09Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-3cdf224b0b734e0faf658af60a7344272023-11-23T09:48:17ZengMDPI AGAntibiotics2079-63822022-04-0111559210.3390/antibiotics11050592Hydroxyapatite/TiO<sub>2</sub> Nanomaterial with Defined Microstructural and Good Antimicrobial PropertiesMiljana Mirković0Suzana Filipović1Ana Kalijadis2Pavle Mašković3Jelena Mašković4Branislav Vlahović5Vladimir Pavlović6Department of Materials, University of Belgrade, “Vinča” Institute of Nuclear Sciences—National Institute of the Republic of Serbia, 11000 Belgrade, SerbiaInstitute of Technical Sciences of SASA, KnezMihailova 35/IV, 11000 Belgrade, SerbiaDepartment of Materials, University of Belgrade, “Vinča” Institute of Nuclear Sciences—National Institute of the Republic of Serbia, 11000 Belgrade, SerbiaFaculty of Agronomy in Čačak, University of Kragujevac, Cara Dušana 34, 32012 Čačak, SerbiaFaculty of Agronomy in Čačak, University of Kragujevac, Cara Dušana 34, 32012 Čačak, SerbiaDepartment of Mathematics and Physics, North Carolina Central University, Durham, NC 27707, USADepartment for Physics and Mathematics, Faculty of Agriculture, University of Belgrade, 11000 Belgrade, SerbiaDue to the growing number of people infected with the new coronavirus globally, which weakens immunity, there has been an increase in bacterial infections. Hence, knowledge about simple and low-cost synthesis methods of materials with good structural and antimicrobial properties is of great importance. A material obtained through the combination of a nanoscale hydroxyapatite material (with good biocompatibility) and titanium dioxide (with good degradation properties of organic molecules) can absorb and decompose bacteria. In this investigation, three different synthesis routes used to prepare hydroxyapatite/titanium dioxide nanomaterials are examined. The morphology and semiquantitative chemical composition are characterized by scanning electron microscopy with energy dispersive X-ray analysis (SEM-EDX). The obtained materials’ phase and structural characterization are determined using the X-ray powder diffraction method (XRD). The crystallite sizes of the obtained materials are in the range of 8 nm to 15 nm. Based on XRD peak positions, the hexagonal hydroxyapatite phases are formed in all samples along with TiO<sub>2</sub> anatase and rutile phases. According to SEM and TEM analyses, the morphology of the prepared samples differs depending on the synthesis route. The EDX analysis confirmed the presence of Ti, Ca, P, and O in the obtained materials. The IR spectroscopy verified the vibration bands characteristic for HAp and titanium. The investigated materials show excellent antimicrobial and photocatalytic properties.https://www.mdpi.com/2079-6382/11/5/592hydroxyapatiteTiO<sub>2</sub>nanomaterialscore–shellantimicrobial |
| spellingShingle | Miljana Mirković Suzana Filipović Ana Kalijadis Pavle Mašković Jelena Mašković Branislav Vlahović Vladimir Pavlović Hydroxyapatite/TiO<sub>2</sub> Nanomaterial with Defined Microstructural and Good Antimicrobial Properties Antibiotics hydroxyapatite TiO<sub>2</sub> nanomaterials core–shell antimicrobial |
| title | Hydroxyapatite/TiO<sub>2</sub> Nanomaterial with Defined Microstructural and Good Antimicrobial Properties |
| title_full | Hydroxyapatite/TiO<sub>2</sub> Nanomaterial with Defined Microstructural and Good Antimicrobial Properties |
| title_fullStr | Hydroxyapatite/TiO<sub>2</sub> Nanomaterial with Defined Microstructural and Good Antimicrobial Properties |
| title_full_unstemmed | Hydroxyapatite/TiO<sub>2</sub> Nanomaterial with Defined Microstructural and Good Antimicrobial Properties |
| title_short | Hydroxyapatite/TiO<sub>2</sub> Nanomaterial with Defined Microstructural and Good Antimicrobial Properties |
| title_sort | hydroxyapatite tio sub 2 sub nanomaterial with defined microstructural and good antimicrobial properties |
| topic | hydroxyapatite TiO<sub>2</sub> nanomaterials core–shell antimicrobial |
| url | https://www.mdpi.com/2079-6382/11/5/592 |
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