Elimination and irrigation therapy to optimize the state of the nasal microbiome in children
The article summarizes the results of the work of domestic and foreign researchers on the study of homeostasis of the nasal cavity, including the state of the microbiota of the nasal mucosa in healthy children and in inflammatory diseases of the upper respiratory tract. The normal microbiota of the...
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2021-03-01
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| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/6027 |
| _version_ | 1797841489114431488 |
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| author | Olga E. Chelpachenko Elena I. Danilova Irina N. Chainikova |
| author_facet | Olga E. Chelpachenko Elena I. Danilova Irina N. Chainikova |
| author_sort | Olga E. Chelpachenko |
| collection | DOAJ |
| description | The article summarizes the results of the work of domestic and foreign researchers on the study of homeostasis of the nasal cavity, including the state of the microbiota of the nasal mucosa in healthy children and in inflammatory diseases of the upper respiratory tract. The normal microbiota of the nasal cavity is represented by corynebacteria (diphtheroids), neisseria, coagulasenegative staphylococci, alpha-hemolytic streptococci. From among the transient species, such species as Staphylococcus aureus, Escherihia coli, beta-hemolytic streptococci would be found in the specified biotope. The main attention is paid to the features of the nasal microbiota in newborns and young children (dependence of the nasal microbiota on the type of feeding, age and season). The role of hypercolonization by opportunistic microflora and its persistent potential (ability to biofilm formation, degradation of lysozyme, interferon) in the pathogenesis of inflammatory diseases of the upper respiratory tract is noted. The pathogenetic mechanisms providing multilevel protection of the organism from pathogens are considered. The expediency of using elimination-irrigation therapy as a hygienic means of sanitizing the nasal cavity in young children has been determined. The questions about the advantages of the use of isotonic solutions, their effectiveness for ensuring normal colonization resistance of the nasal mucosa are discussed. In conclusion, we must say that for hygienic care and sanitation purposes it is recommended only to rinse the nasal mucosa in newborns and infants using drops of isotonic saline solution and an aspirator to avoid aspiration and inflow of liquid into the cavity of Eustachian tube and middle ear, and also for the preventive purposes, as it allows to maintain homeostasis of the nasal mucosa and prevent the development of acute respiratory diseases. |
| first_indexed | 2024-04-09T16:31:40Z |
| format | Article |
| id | doaj.art-3cdf89fb5dc54a5b9ca94c0d8af756a0 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:31:40Z |
| publishDate | 2021-03-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-3cdf89fb5dc54a5b9ca94c0d8af756a02023-04-23T06:57:03ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902021-03-0101505810.21518/2079-701X-2021-1-50-585476Elimination and irrigation therapy to optimize the state of the nasal microbiome in childrenOlga E. Chelpachenko0Elena I. Danilova1Irina N. Chainikova2Institute of Cellular and Intracellular Symbiosis, Ural Branch of RASOrenburg State Medical UniversityInstitute of Cellular and Intracellular Symbiosis, Ural Branch of RAS; Orenburg State Medical UniversityThe article summarizes the results of the work of domestic and foreign researchers on the study of homeostasis of the nasal cavity, including the state of the microbiota of the nasal mucosa in healthy children and in inflammatory diseases of the upper respiratory tract. The normal microbiota of the nasal cavity is represented by corynebacteria (diphtheroids), neisseria, coagulasenegative staphylococci, alpha-hemolytic streptococci. From among the transient species, such species as Staphylococcus aureus, Escherihia coli, beta-hemolytic streptococci would be found in the specified biotope. The main attention is paid to the features of the nasal microbiota in newborns and young children (dependence of the nasal microbiota on the type of feeding, age and season). The role of hypercolonization by opportunistic microflora and its persistent potential (ability to biofilm formation, degradation of lysozyme, interferon) in the pathogenesis of inflammatory diseases of the upper respiratory tract is noted. The pathogenetic mechanisms providing multilevel protection of the organism from pathogens are considered. The expediency of using elimination-irrigation therapy as a hygienic means of sanitizing the nasal cavity in young children has been determined. The questions about the advantages of the use of isotonic solutions, their effectiveness for ensuring normal colonization resistance of the nasal mucosa are discussed. In conclusion, we must say that for hygienic care and sanitation purposes it is recommended only to rinse the nasal mucosa in newborns and infants using drops of isotonic saline solution and an aspirator to avoid aspiration and inflow of liquid into the cavity of Eustachian tube and middle ear, and also for the preventive purposes, as it allows to maintain homeostasis of the nasal mucosa and prevent the development of acute respiratory diseases.https://www.med-sovet.pro/jour/article/view/6027homeostasisnasal cavitynasal microbiotaelimination-irrigation therapyisotonic saline solutionsyoung children |
| spellingShingle | Olga E. Chelpachenko Elena I. Danilova Irina N. Chainikova Elimination and irrigation therapy to optimize the state of the nasal microbiome in children Медицинский совет homeostasis nasal cavity nasal microbiota elimination-irrigation therapy isotonic saline solutions young children |
| title | Elimination and irrigation therapy to optimize the state of the nasal microbiome in children |
| title_full | Elimination and irrigation therapy to optimize the state of the nasal microbiome in children |
| title_fullStr | Elimination and irrigation therapy to optimize the state of the nasal microbiome in children |
| title_full_unstemmed | Elimination and irrigation therapy to optimize the state of the nasal microbiome in children |
| title_short | Elimination and irrigation therapy to optimize the state of the nasal microbiome in children |
| title_sort | elimination and irrigation therapy to optimize the state of the nasal microbiome in children |
| topic | homeostasis nasal cavity nasal microbiota elimination-irrigation therapy isotonic saline solutions young children |
| url | https://www.med-sovet.pro/jour/article/view/6027 |
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