Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
In label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07723-8 |
| _version_ | 1818428645266423808 |
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| author | Stefano Mariani Valentina Robbiano Lucanos M. Strambini Aline Debrassi Gabriela Egri Lars Dähne Giuseppe Barillaro |
| author_facet | Stefano Mariani Valentina Robbiano Lucanos M. Strambini Aline Debrassi Gabriela Egri Lars Dähne Giuseppe Barillaro |
| author_sort | Stefano Mariani |
| collection | DOAJ |
| description | In label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva. |
| first_indexed | 2024-12-14T15:04:55Z |
| format | Article |
| id | doaj.art-3ce1e64ca68a4c3ca778db24344f2c7b |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T15:04:55Z |
| publishDate | 2018-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-3ce1e64ca68a4c3ca778db24344f2c7b2022-12-21T22:56:43ZengNature PortfolioNature Communications2041-17232018-12-019111310.1038/s41467-018-07723-8Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensingStefano Mariani0Valentina Robbiano1Lucanos M. Strambini2Aline Debrassi3Gabriela Egri4Lars Dähne5Giuseppe Barillaro6Dipartimento di Ingegneria dell’Informazione, Università di PisaDipartimento di Ingegneria dell’Informazione, Università di PisaIstituto di Elettronica e di Ingegneria dell’Informazione e delle Telecomunicazioni, Consiglio Nazionale delle RicercheSurflay Nanotec GmbHSurflay Nanotec GmbHSurflay Nanotec GmbHDipartimento di Ingegneria dell’Informazione, Università di PisaIn label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.https://doi.org/10.1038/s41467-018-07723-8 |
| spellingShingle | Stefano Mariani Valentina Robbiano Lucanos M. Strambini Aline Debrassi Gabriela Egri Lars Dähne Giuseppe Barillaro Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing Nature Communications |
| title | Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing |
| title_full | Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing |
| title_fullStr | Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing |
| title_full_unstemmed | Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing |
| title_short | Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing |
| title_sort | layer by layer biofunctionalization of nanostructured porous silicon for high sensitivity and high selectivity label free affinity biosensing |
| url | https://doi.org/10.1038/s41467-018-07723-8 |
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