Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation
Ascending aorta coarctation was produced by a minimally invasive technique in rabbits. Animal mortality was 5%. Morphometric and hemodynamic parameters were evaluated. A parabiotically isolated heart model was used to assess the hemodynamic parameters. Left ventricular weight/body weight ratio and m...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Divulgação Científica
2001-01-01
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| Series: | Brazilian Journal of Medical and Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300017 |
| _version_ | 1818386742590308352 |
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| author | Martins A.S. Aguilera N.W. Matsubara B.B. Bregagnollo E.A. |
| author_facet | Martins A.S. Aguilera N.W. Matsubara B.B. Bregagnollo E.A. |
| author_sort | Martins A.S. |
| collection | DOAJ |
| description | Ascending aorta coarctation was produced by a minimally invasive technique in rabbits. Animal mortality was 5%. Morphometric and hemodynamic parameters were evaluated. A parabiotically isolated heart model was used to assess the hemodynamic parameters. Left ventricular weight/body weight ratio and muscle area showed clear evidence of hypertrophy when compared to control. The hemodynamic changes in the isolated heart model suggested decreased diastolic and systolic function in the coarcted group. The present model produced hypertrophy with low mortality rates as a result of its less invasive nature. |
| first_indexed | 2024-12-14T03:58:53Z |
| format | Article |
| id | doaj.art-3ce412ce2fbb4235bf752e2b0bdbac6f |
| institution | Directory Open Access Journal |
| issn | 0100-879X 0034-7310 |
| language | English |
| last_indexed | 2024-12-14T03:58:53Z |
| publishDate | 2001-01-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-3ce412ce2fbb4235bf752e2b0bdbac6f2022-12-21T23:18:00ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research0100-879X0034-73102001-01-01343413415Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctationMartins A.S.Aguilera N.W.Matsubara B.B.Bregagnollo E.A.Ascending aorta coarctation was produced by a minimally invasive technique in rabbits. Animal mortality was 5%. Morphometric and hemodynamic parameters were evaluated. A parabiotically isolated heart model was used to assess the hemodynamic parameters. Left ventricular weight/body weight ratio and muscle area showed clear evidence of hypertrophy when compared to control. The hemodynamic changes in the isolated heart model suggested decreased diastolic and systolic function in the coarcted group. The present model produced hypertrophy with low mortality rates as a result of its less invasive nature.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300017ventricular hypertrophyventricular functionexperimental model |
| spellingShingle | Martins A.S. Aguilera N.W. Matsubara B.B. Bregagnollo E.A. Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation Brazilian Journal of Medical and Biological Research ventricular hypertrophy ventricular function experimental model |
| title | Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation |
| title_full | Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation |
| title_fullStr | Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation |
| title_full_unstemmed | Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation |
| title_short | Experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation |
| title_sort | experimental myocardial hypertrophy induced by a minimally invasive ascending aorta coarctation |
| topic | ventricular hypertrophy ventricular function experimental model |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300017 |
| work_keys_str_mv | AT martinsas experimentalmyocardialhypertrophyinducedbyaminimallyinvasiveascendingaortacoarctation AT aguileranw experimentalmyocardialhypertrophyinducedbyaminimallyinvasiveascendingaortacoarctation AT matsubarabb experimentalmyocardialhypertrophyinducedbyaminimallyinvasiveascendingaortacoarctation AT bregagnolloea experimentalmyocardialhypertrophyinducedbyaminimallyinvasiveascendingaortacoarctation |